Quantifying Crosstalk Among Interferon-γ, Interleukin-12 and Tumor Necrosis Factor Signaling Pathways Within a T(H)1 Cell Model

Por Klinke, David J., Cheng, Ning, Chambers, Emily
Publicado em 2012

Application of a Bioinformatics-Based Approach to Identify Novel Putative in vivo BACE1 Substrates

Por Johnson, Joseph L, Chambers, Emily, Jayasundera, Keerthi
Publicado em 2013

Opening sequence: computational genomics in the era of high-throughput sequencing

Por Chambers, Emily V, Kindt, Alida S, Semple, Colin AM
Publicado em 2011

Divergence of Mammalian Higher Order Chromatin Structure Is Associated with Developmental Loci

Por Chambers, Emily V., Bickmore, Wendy A., Semple, Colin A.
Publicado em 2013

Brain MRI Phenotypes Associated with Polymorphisms at or Near the SLC39A8 (ZIP8) Metal Transporter Gene

Por Hermann, Evan, Chambers, Emily, Davis, Danielle, Montgomery, Mckale, Chowanadisai, Winyoo
Publicado no Curr Dev Nutr (2020)

Sequence-Level Mechanisms of Human Epigenome Evolution

Por Prendergast, James G.D., Chambers, Emily V., Semple, Colin A.M.
Publicado em 2014

Brain MRI Phenotypes Associated with Polymorphisms at or near the MAPT (Microtubule Associated Protein Tau) and COASY (Coenzyme A Synthase) Genes

Por Chambers, Emily, Hermann, Evan, Davis, Danielle, Montgomery, Mckale, Lucas, Edralin, Chowanadisai, Winyoo
Publicado no Curr Dev Nutr (2020)

Coding Polymorphisms in Zinc Transporter Gene SLC39A12 (ZIP12) Associated with Brain MRI Pattern Differences Have Reduced Zinc Transport Activity

Por Chambers, Emily, Clarke, Stephen, Lucas, Edralin, Lucas, Edralin, Stoeker, Barbara, Chowanadisai, Winyoo, Bettaieb, Ahmed, Agidew, Worknah
Publicado no Curr Dev Nutr (2020)

Brain Magnetic Resonance Imaging Phenome-Wide Association Study With Metal Transporter Gene SLC39A8

Por Hermann, Evan R., Chambers, Emily, Davis, Danielle N., Montgomery, McKale R., Lin, Dingbo, Chowanadisai, Winyoo
Publicado no Front Genet (2021)

A quantitative systems approach to identify paracrine mechanisms that locally suppress immune response to Interleukin-12 in the B16 melanoma model

Por Kulkarni, Yogesh M., Chambers, Emily, McGray, A. J. Robert, Ware, Jason S., Bramson, Jonathan L., Klinke, David J.
Publicado em 2012

Identification of Differential Gene Expression in Brassica rapa Nectaries through Expressed Sequence Tag Analysis

Por Hampton, Marshall, Xu, Wayne W., Kram, Brian W., Chambers, Emily M., Ehrnriter, Jerad S., Gralewski, Jonathan H., Joyal, Teresa, Carter, Clay J.
Publicado em 2010

Immune-related response assessment during PD-1 inhibitor therapy in advanced non-small-cell lung cancer patients

Por Nishino, Mizuki, Ramaiya, Nikhil H., Chambers, Emily S., Adeni, Anika E., Hatabu, Hiroto, Jänne, Pasi A., Hodi, F. Stephen, Awad, Mark M.
Publicado no J Immunother Cancer (2016)

Mechanism of PrP‐Amyloid Formation in Mice Without Transmissible Spongiform Encephalopathy

Por Jeffrey, Martin, McGovern, Gillian, Chambers, Emily V., King, Declan, González, Lorenzo, Manson, Jean C., Ghetti, Bernardino, Piccardo, Pedro, Barron, Rona M.
Publicado em 2011

Anti–PD-1 inhibitor–related pneumonitis in non–small cell lung cancer

Por Nishino, Mizuki, Chambers, Emily S., Chong, Curtis R., Ramaiya, Nikhil H., Gray, Stacy W., Marcoux, J. Paul, Hatabu, Hiroto, Jänne, Pasi A., Hodi, F. Stephen, Awad, Mark M.
Publicado no Cancer Immunol Res (2016)

Identification of a RAS-activating TMEM87A-RASGRF1 fusion in an exceptional responder to sunitinib with non-small cell lung cancer

Por Cooper, Alissa J, Kobayashi, Yoshihisa, Kim, Dewey, Clifford, Sarah E, Kravets, Sasha, Dahlberg, Suzanne E, Chambers, Emily S, Li, Jiaqi, Rangachari, Deepa, Nguyen, Tom, Costa, Daniel B, Rabin, Michael S, Wagle, Nikhil, Sholl, Lynette M, Jänne, Pasi A, Oxnard, Geoffrey R
Publicado no Clin Cancer Res (2020)

Genomic and pathological heterogeneity in clinically diagnosed small cell lung cancer in never/light smokers identifies therapeutically targetable alterations

Por Ogino, Atsuko, Choi, Jihyun, Lin, Mika, Wilkens, Margaret K., Calles, Antonio, Xu, Man, Adeni, Anika E., Chambers, Emily S., Capelletti, Marzia, Butaney, Mohit, Gray, Nathanael S., Gokhale, Prafulla C., Palakurthi, Sangeetha, Kirschmeier, Paul, Oxnard, Geoffrey R., Sholl, Lynette M., Jänne, Pasi A.
Publicado no Mol Oncol (2020)

ERK inhibitor LY3214996-based treatment strategies for RAS-driven lung cancer

Por Köhler, Jens, Zhao, Yutong, Li, Jiaqi, Gokhale, Prafulla C., Tiv, Hong L., Knott, Aine R., Wilkens, Margaret K., Soroko, Kara M., Lin, Mika, Ambrogio, Chiara, Musteanu, Monica, Ogino, Atsuko, Choi, Jihyun, Bahcall, Magda, Bertram, Arrien A., Chambers, Emily S., Paweletz, Cloud P., Bhagwat, Shripad V., Manro, Jason R., Tiu, Ramon V., Jänne, Pasi A.
Publicado no Mol Cancer Ther (2021)

Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action

Por McFarland, James M., Paolella, Brenton R., Warren, Allison, Geiger-Schuller, Kathryn, Shibue, Tsukasa, Rothberg, Michael, Kuksenko, Olena, Colgan, William N., Jones, Andrew, Chambers, Emily, Dionne, Danielle, Bender, Samantha, Wolpin, Brian M., Ghandi, Mahmoud, Tirosh, Itay, Rozenblatt-Rosen, Orit, Roth, Jennifer A., Golub, Todd R., Regev, Aviv, Aguirre, Andrew J., Vazquez, Francisca, Tsherniak, Aviad
Publicado no Nat Commun (2020)

Use of ex vivo patient derived tumor organotypic spheroids to identify combination therapies for HER2 mutant non small cell lung cancer

Por Ivanova, Elena, Kuraguchi, Mari, Xu, Man, Portell, Andrew J., Taus, Luke, Diala, Irmina, Lalani, Alshad S., Choi, Jihyun, Chambers, Emily S., Li, Shuai, Liu, Shengwu, Chen, Ting, Barbie, Thanh U., Oxnard, Geoffrey R., Haworth, Jacob J, Wong, Kwok-Kin, Dahlberg, Suzanne E., Aref, Amir A., Barbie, David A., Bahcall, Magda, Paweletz, Cloud P., Jänne, Pasi A.
Publicado no Clin Cancer Res (2020)

Amplification of wild type KRAS imparts resistance to crizotinib in MET exon 14 mutant non-small cell lung cancer

Por Bahcall, Magda, Awad, Mark M., Sholl, Lynette M., Wilson, Frederick H., Xu, Man, Wang, Stephen, Palakurthi, Sangeetha, Choi, Jihyun, Ivanova, Elena V., Leonardi, Giulia C., Ulrich, Bryan C., Paweletz, Cloud P., Kirschmeier, Paul T., Watanabe, Masayuki, Baba, Hideo, Nishino, Mizuki, Nagy, Rebecca J., Lanman, Richard B., Capelletti, Marzia, Chambers, Emily S., Redig, Amanda J., VanderLaan, Paul A., Costa, Daniel B., Imamura, Yu, Jänne, Pasi A.
Publicado no Clin Cancer Res (2018)