Breast cancer genome heterogeneity: a challenge to personalised medicine?

Por Swanton, Charles, Burrell, Rebecca A, Futreal, P Andrew
Publicado em 2011

Effects of Co-Varying Diel-Cycling Hypoxia and pH on Growth in the Juvenile Eastern Oyster, Crassostrea virginica

Por Keppel, Andrew G., Breitburg, Denise L., Burrell, Rebecca B.
Publicado no PLoS One (2016)

Cancer chromosomal instability: therapeutic and diagnostic challenges

Por McGranahan, Nicholas, Burrell, Rebecca A, Endesfelder, David, Novelli, Marco R, Swanton, Charles
Publicado em 2012

Landscape-Level Variation in Disease Susceptibility Related to Shallow-Water Hypoxia

Por Breitburg, Denise L., Hondorp, Darryl, Audemard, Corinne, Carnegie, Ryan B., Burrell, Rebecca B., Trice, Mark, Clark, Virginia
Publicado no PLoS One (2015)

Chromosomal instability selects gene copy number variants encoding core regulators of proliferation in ER+ breast cancer

Por Endesfelder, David, Burrell, Rebecca, Kanu, Nnennaya, McGranahan, Nicholas, Howell, Mike, Parker, Peter J., Downward, Julian, Swanton, Charles, Kschischo, Maik
Publicado em 2014

RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress

Por Kanu, Nnennaya, Zhang, Tianyi, Burrell, Rebecca A., Chakraborty, Atanu, Cronshaw, Janet, Da Costa, Clive, Grönroos, Eva, Pemberton, Helen N., Anderton, Emma, Gonzalez, Laure, Sabbioneda, Simone, Ulrich, Helle D., Swanton, Charles, Behrens, Axel
Publicado no Oncogene (2015)

Relationship of Extreme Chromosomal Instability with Long-term Survival in a Retrospective Analysis of Primary Breast Cancer

Por Roylance, Rebecca, Endesfelder, David, Gorman, Patricia, Burrell, Rebecca A., Sander, Jil, Tomlinson, Ian, Hanby, Andrew M, Speirs, Valerie, Richardson, Andrea L., Birkbak, Nicolai J., Eklund, Aron C., Downward, Julian, Kschischo, Maik, Szallasi, Zoltan, Swanton, Charles
Publicado em 2011

Tolerance whole of genome doubling propagates chromosomal instability and accelerates cancer genome evolution

Por Dewhurst, Sally M, McGranahan, Nicholas, Burrell, Rebecca A, Rowan, Andrew J, Grönroos, Eva, Endesfelder, David, Joshi, Tejal, Mouradov, Dmitri, Gibbs, Peter, Ward, Robyn L., Hawkins, Nicholas J., Szallasi, Zoltan, Sieber, Oliver M., Swanton, Charles
Publicado no Cancer Discov (2014)

Genome-wide RNA interference analysis of renal carcinoma survival regulators identifies MCT4 as a Warburg effect metabolic target

Por Gerlinger, Marco, Santos, Claudio R, Spencer-Dene, Bradley, Martinez, Pierre, Endesfelder, David, Burrell, Rebecca A, Vetter, Marcus, Jiang, Ming, Saunders, Rebecca E, Kelly, Gavin, Dykema, Karl, Rioux-Leclercq, Nathalie, Stamp, Gordon, Patard, Jean Jacques, Larkin, James, Howell, Michael, Swanton, Charles
Publicado em 2012

Replication stress links structural and numerical cancer chromosomal instability

Por Burrell, Rebecca A., McClelland, Sarah E., Endesfelder, David, Groth, Petra, Weller, Marie-Christine, Shaikh, Nadeem, Domingo, Enric, Kanu, Nnennaya, Dewhurst, Sally M., Gronroos, Eva, Chew, Su Kit, Rowan, Andrew J., Schenk, Arne, Sheffer, Michal, Howell, Michael, Kschischo, Maik, Behrens, Axel, Helleday, Thomas, Bartek, Jiri, Tomlinson, Ian P., Swanton, Charles
Publicado no Nature (2013)

BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer

Por López-García, Carlos, Sansregret, Laurent, Domingo, Enric, McGranahan, Nicholas, Hobor, Sebastijan, Birkbak, Nicolai Juul, Horswell, Stuart, Grönroos, Eva, Favero, Francesco, Rowan, Andrew J., Matthews, Nicholas, Begum, Sharmin, Phillimore, Benjamin, Burrell, Rebecca, Oukrif, Dahmane, Spencer-Dene, Bradley, Kovac, Michal, Stamp, Gordon, Stewart, Aengus, Danielsen, Havard, Novelli, Marco, Tomlinson, Ian, Swanton, Charles
Publicado no Cancer Cell (2017)