RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress

The DNA replication machinery invariably encounters obstacles that slow replication fork progression, and threaten to prevent complete replication and faithful segregation of sister chromatids. The resulting replication stress activates ATR, the major kinase involved in resolving impaired DNA replic...

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Bibliographic Details
Published in:Oncogene
Main Authors: Kanu, Nnennaya, Zhang, Tianyi, Burrell, Rebecca A., Chakraborty, Atanu, Cronshaw, Janet, Da Costa, Clive, Grönroos, Eva, Pemberton, Helen N., Anderton, Emma, Gonzalez, Laure, Sabbioneda, Simone, Ulrich, Helle D., Swanton, Charles, Behrens, Axel
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4842010/
https://ncbi.nlm.nih.gov/pubmed/26549024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.427
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