ロード中...
Inactivation of the ATMIN/ATM pathway protects against glioblastoma formation
Glioblastoma multiforme (GBM) is the most aggressive human primary brain cancer. Using a Trp53-deficient mouse model of GBM, we show that genetic inactivation of the Atm cofactor Atmin, which is dispensable for embryonic and adult neural development, strongly suppresses GBM formation. Mechanisticall...
保存先:
| 出版年: | eLife |
|---|---|
| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
eLife Sciences Publications, Ltd
2016
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4811777/ https://ncbi.nlm.nih.gov/pubmed/26984279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08711 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|