Replication stress links structural and numerical cancer chromosomal instability

Cancer chromosomal instability (CIN) results in an elevated rate of change of chromosome number and structure and generates intratumour heterogeneity(1,2). CIN is observed in the majority of solid tumours and is associated with both poor prognosis and drug resistance(3,4). Therefore, understanding a...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Nature
मुख्य लेखकों: Burrell, Rebecca A., McClelland, Sarah E., Endesfelder, David, Groth, Petra, Weller, Marie-Christine, Shaikh, Nadeem, Domingo, Enric, Kanu, Nnennaya, Dewhurst, Sally M., Gronroos, Eva, Chew, Su Kit, Rowan, Andrew J., Schenk, Arne, Sheffer, Michal, Howell, Michael, Kschischo, Maik, Behrens, Axel, Helleday, Thomas, Bartek, Jiri, Tomlinson, Ian P., Swanton, Charles
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2013
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636055/
https://ncbi.nlm.nih.gov/pubmed/23446422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11935
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