Chromosomal Instability Confers Intrinsic Multi-Drug Resistance

Aneuploidy is associated with poor prognosis in solid tumours. Spontaneous chromosome mis-segregation events in aneuploid cells promote Chromosomal Instability (CIN) that may contribute to the acquisition of multi-drug resistance in vitro and heighten risk for tumour relapse in animal models. Identi...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Lee, Alvin J X, Endesfelder, David, Rowan, Andrew J, Walther, Axel, Birkbak, Nicolai J, Futreal, P Andrew, Downward, Julian, Szallasi, Zoltan, Tomlinson, Ian P M, Kschischo, Maik, Swanton, Charles
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059493/
https://ncbi.nlm.nih.gov/pubmed/21363922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-3604
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi