Chromosomal instability determines taxane response

Microtubule-stabilizing (MTS) agents, such as taxanes, are important chemotherapeutics with a poorly understood mechanism of action. We identified a set of genes repressed in multiple cell lines in response to MTS agents and observed that these genes are overexpressed in tumors exhibiting chromosoma...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Swanton, Charles, Nicke, Barbara, Schuett, Marion, Eklund, Aron C., Ng, Charlotte, Li, Qiyuan, Hardcastle, Thomas, Lee, Alvin, Roy, Rajat, East, Philip, Kschischo, Maik, Endesfelder, David, Wylie, Paul, Kim, Se Nyun, Chen, Jie-Guang, Howell, Michael, Ried, Thomas, Habermann, Jens K., Auer, Gert, Brenton, James D., Szallasi, Zoltan, Downward, Julian
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2009
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688979/
https://ncbi.nlm.nih.gov/pubmed/19458043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811835106
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky