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Functional genomic analysis of drug sensitivity pathways to guide adjuvant strategies in breast cancer

The widespread introduction of high throughput RNA interference screening technology has revealed tumour drug sensitivity pathways to common cytotoxics such as paclitaxel, doxorubicin and 5-fluorouracil, targeted agents such as trastuzumab and inhibitors of AKT and Poly(ADP-ribose) polymerase (PARP)...

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Detalhes bibliográficos
Main Authors: Swanton, Charles, Szallasi, Zoltan, Brenton, James D, Downward, Julian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614525/
https://ncbi.nlm.nih.gov/pubmed/18986507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2159
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