Functional genomic analysis of drug sensitivity pathways to guide adjuvant strategies in breast cancer

The widespread introduction of high throughput RNA interference screening technology has revealed tumour drug sensitivity pathways to common cytotoxics such as paclitaxel, doxorubicin and 5-fluorouracil, targeted agents such as trastuzumab and inhibitors of AKT and Poly(ADP-ribose) polymerase (PARP)...

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Main Authors: Swanton, Charles, Szallasi, Zoltan, Brenton, James D, Downward, Julian
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2008
Teme:
Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614525/
https://ncbi.nlm.nih.gov/pubmed/18986507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2159
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