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Quantitative phenotypic and pathway profiling guides rational drug combination strategies

Advances in target-based drug discovery strategies have enabled drug discovery groups in academia and industry to become very effective at generating molecules that are potent and selective against single targets. However, it has become apparent from disappointing results in recent clinical trials t...

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מידע ביבליוגרפי
Main Authors: Dawson, John C., Carragher, Neil O.
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035564/
https://ncbi.nlm.nih.gov/pubmed/24904421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00118
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