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Quantitative phenotypic and pathway profiling guides rational drug combination strategies

Advances in target-based drug discovery strategies have enabled drug discovery groups in academia and industry to become very effective at generating molecules that are potent and selective against single targets. However, it has become apparent from disappointing results in recent clinical trials t...

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Bibliografiske detaljer
Main Authors: Dawson, John C., Carragher, Neil O.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035564/
https://ncbi.nlm.nih.gov/pubmed/24904421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00118
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