Stress-Responsive Sestrins Link p53 with Redox Regulation and Mammalian Target of Rapamycin Signaling

Por Budanov, Andrei V.
Publicado em 2011

The role of tumor suppressor p53 in the antioxidant defense and metabolism

Por Budanov, Andrei V.
Publicado em 2014

SESTRINs regulate mTORC1 via RRAGs: The riddle of GATOR

Por Budanov, Andrei V
Publicado no Mol Cell Oncol (2015)

The p53-regulated Sestrin gene products inhibit mTOR signaling

Por Budanov, Andrei V., Karin, Michael
Publicado em 2008

Stressin' Sestrins take an aging fight

Por Budanov, Andrei V, Lee, Jun Hee, Karin, Michael
Publicado em 2010

Sestrins orchestrate cellular metabolism to attenuate aging

Por Lee, Jun Hee, Budanov, Andrei V., Karin, Michael
Publicado em 2013

Sestrin2 facilitates death receptor-induced apoptosis in lung adenocarcinoma cells through regulation of XIAP degradation

Por Ding, Boxiao, Parmigiani, Anita, Yang, Chen, Budanov, Andrei V
Publicado no Cell Cycle (2015)

Sestrin2 is induced by glucose starvation via the unfolded protein response and protects cells from non-canonical necroptotic cell death

Por Ding, Boxiao, Parmigiani, Anita, Divakaruni, Ajit S., Archer, Kellie, Murphy, Anne N., Budanov, Andrei V.
Publicado no Sci Rep (2016)

Implication of KRT16, FAM129A and HKDC1 genes as ATF4 regulated components of the integrated stress response

Por Evstafieva, Alexandra G., Kovaleva, Irina E., Shoshinova, Maria S., Budanov, Andrei V., Chumakov, Peter M.
Publicado no PLoS One (2018)

The antioxidant function of the p53 tumor suppressor

Por Sablina, Anna A., Budanov, Andrei V., Ilyinskaya, Galina V., Agapova, Larissa S., Kravchenko, Julia E., Chumakov, Peter M.
Publicado em 2005

Sestrin2 Protein Positively Regulates AKT Enzyme Signaling and Survival in Human Squamous Cell Carcinoma and Melanoma Cells

Por Zhao, Baozhong, Shah, Palak, Budanov, Andrei V., Qiang, Lei, Ming, Mei, Aplin, Andrew, Sims, Diane M., He, Yu-Ying
Publicado no J Biol Chem (2014)

Sestrins Inhibit mTORC1 Kinase Activation Through the GATOR Complex

Por Parmigiani, Anita, Nourbakhsh, Aida, Ding, Boxiao, Wang, Wei, Kim, Young Chul, Akopiants, Konstantin, Guan, Kun-Liang, Karin, Michael, Budanov, Andrei V.
Publicado no Cell Rep (2014)

Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies

Por Lee, Jun Hee, Budanov, Andrei V., Park, Eek Joong, Birse, Ryan, Kim, Teddy E., Perkins, Guy A., Ocorr, Karen, Ellisman, Mark H., Bodmer, Rolf, Bier, Ethan, Karin, Michael
Publicado em 2010

Maintenance of metabolic homeostasis by Sestrin 2 and 3

Por Lee, Jun Hee, Budanov, Andrei V., Talukdar, Saswata, Park, Eek Joong, Park, Hae Li, Park, Hwan-Woo, Bandyopadhyay, Gautam, Li, Ning, Aghajan, Mariam, Jang, Insook, Wolfe, Amber M., Perkins, Guy A., Ellisman, Mark H., Bier, Ethan, Scadeng, Miriam, Foretz, Marc, Viollet, Benoit, Olefsky, Jerrold, Karin, Michael
Publicado em 2012

Genetic and epigenetic inactivation of SESTRIN1 controls mTORC1 and response to EZH2 inhibition in follicular lymphoma

Por Oricchio, Elisa, Katanayeva, Natalya, Donaldson, Maria Christine, Sungalee, Stephanie, Pasion, Joyce P., Béguelin, Wendy, Battistello, Elena, Sanghvi, Viraj R., Jiang, Man, Jiang, Yanwen, Teater, Matt, Parmigiani, Anita, Budanov, Andrei V., Chan, Fong Chun, Shah, Sohrab P., Kridel, Robert, Melnick, Ari M., Ciriello, Giovanni, Wendel, Hans-Guido
Publicado no Sci Transl Med (2017)