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Sestrins orchestrate cellular metabolism to attenuate aging

The Sestrins constitute a family of evolutionarily-conserved stress-inducible proteins that suppress oxidative stress and regulate adenosine monophosphate-dependent protein kinase (AMPK)-mammalian target of rapamycin (mTOR) signaling. By virtue of these activities, the Sestrins serve as important re...

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Bibliografische gegevens
Hoofdauteurs: Lee, Jun Hee, Budanov, Andrei V., Karin, Michael
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858445/
https://ncbi.nlm.nih.gov/pubmed/24055102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.08.018
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