Genetic and Molecular Basis of Inflammasome-mediated Disease

Por Hoffman, Hal M., Brydges, Susannah D.
Publicado em 2011

Autoinflammation: translating mechanism to therapy

Por Doherty, Taylor A., Brydges, Susannah D., Hoffman, Hal M.
Publicado em 2011

A transient forward targeting element for microneme regulated secretion in Toxoplasma gondii

Por Brydges, Susannah D., Harper, Jill M., Parussini, Fabiola, Coppens, Isabelle, Carruthers, Vern B.
Publicado em 2008

Divergence of IL-1, IL-18, and cell death in NLRP3 inflammasomopathies

Por Brydges, Susannah D., Broderick, Lori, McGeough, Matthew D., Pena, Carla A., Mueller, James L., Hoffman, Hal M.
Publicado em 2013

Dissolution of Xylose Metabolism in Lactococcus lactis

Por Erlandson, Karn A., Park, Joo-Heon, Wissam, El Khal, Kao, Hsin-Hsin, Basaran, Pervin, Brydges, Susannah, Batt, Carl A.
Publicado em 2000

Interleukin-6 is a Marker of Inflammation with No Direct Role in Inflammasome-Mediated Mouse Models()

Por McGeough, Matthew D., Pena, Carla A., Mueller, James L., Pociask, Derek A., Broderick, Lori, Hoffman, Hal M., Brydges, Susannah D.
Publicado em 2012

Targeted Deletion of MIC5 Enhances Trimming Proteolysis of Toxoplasma Invasion Proteins

Por Brydges, Susannah D., Zhou, Xing Wang, Huynh, My-Hang, Harper, Jill M., Mital, Jeffrey, Adjogble, Koku D. Z., Däubener, Walter, Ward, Gary E., Carruthers, Vern B.
Publicado em 2006

Mouse models of X-linked juvenile retinoschisis have an early onset phenotype, the severity of which varies with genotype

Por Liu, Yang, Kinoshita, Junzo, Ivanova, Elena, Sun, Duo, Li, Hong, Liao, Tara, Cao, Jingtai, Bell, Brent A, Wang, Jacob M, Tang, Yajun, Brydges, Susannah, Peachey, Neal S, Sagdullaev, Botir T, Romano, Carmelo
Publicado no Hum Mol Genet (2019)

Pyrin Modulates the Intracellular Distribution of PSTPIP1

Por Waite, Andrea L., Schaner, Philip, Richards, Neil, Balci-Peynircioglu, Banu, Masters, Seth L., Brydges, Susannah D., Fox, Michelle, Hong, Arthur, Yilmaz, Engin, Kastner, Daniel L., Reinherz, Ellis L., Gumucio, Deborah L.
Publicado em 2009

Animal Models of Inflammasomopathies Reveal Roles for Innate but not Adaptive Immunity

Por Brydges, Susannah D, Mueller, James L, McGeough, Matthew D, Pena, Carla A, Misaghi, Amirhossein, Gandhi, Chhavi, Putnam, Chris D, Boyle, David L, Firestein, Gary S, Horner, Anthony A, Soroosh, Pejman, Watford, Wendy T, O’Shea, John J, Kastner, Daniel L, Hoffman, Hal M
Publicado em 2009

Constitutively Activated NLRP3 Inflammasome Causes Inflammation and Abnormal Skeletal Development in Mice

Por Bonar, Sheri L., Brydges, Susannah D., Mueller, James L., McGeough, Matthew D., Pena, Carla, Chen, Debbie, Grimston, Susan K., Hickman-Brecks, Cynthia L., Ravindran, Soumya, McAlinden, Audrey, Novack, Deborah V., Kastner, Daniel L., Civitelli, Roberto, Hoffman, Hal M., Mbalaviele, Gabriel
Publicado em 2012

C9orf72 ablation causes immune dysregulation characterized by leukocyte expansion, autoantibody production, and glomerulonephropathy in mice

Por Atanasio, Amanda, Decman, Vilma, White, Derek, Ramos, Meg, Ikiz, Burcin, Lee, Hoi-Ching, Siao, Chia-Jen, Brydges, Susannah, LaRosa, Elizabeth, Bai, Yu, Fury, Wen, Burfeind, Patricia, Zamfirova, Ralica, Warshaw, Gregg, Orengo, Jamie, Oyejide, Adelekan, Fralish, Michael, Auerbach, Wojtek, Poueymirou, William, Freudenberg, Jan, Gong, Guochun, Zambrowicz, Brian, Valenzuela, David, Yancopoulos, George, Murphy, Andrew, Thurston, Gavin, Lai, Ka-Man Venus
Publicado no Sci Rep (2016)

Mutations in topoisomerase IIβ result in a B cell immunodeficiency

Por Broderick, Lori, Yost, Shawn, Li, Dong, McGeough, Matthew D., Booshehri, Laela M., Guaderrama, Marisela, Brydges, Susannah D., Kucharova, Karolina, Patel, Niraj C., Harr, Margaret, Hakonarson, Hakon, Zackai, Elaine, Cowell, Ian G., Austin, Caroline A., Hügle, Boris, Gebauer, Corinna, Zhang, Jianguo, Xu, Xun, Wang, Jian, Croker, Ben A., Frazer, Kelly A., Putnam, Christopher D., Hoffman, Hal M.
Publicado no Nat Commun (2019)

Monoallelic BMP2 Variants Predicted to Result in Haploinsufficiency Cause Craniofacial, Skeletal, and Cardiac Features Overlapping Those of 20p12 Deletions

Por Tan, Tiong Yang, Gonzaga-Jauregui, Claudia, Bhoj, Elizabeth J., Strauss, Kevin A., Brigatti, Karlla, Puffenberger, Erik, Li, Dong, Xie, LiQin, Das, Nanditha, Skubas, Ioanna, Deckelbaum, Ron A., Hughes, Virginia, Brydges, Susannah, Hatsell, Sarah, Siao, Chia-Jen, Dominguez, Melissa G., Economides, Aris, Overton, John D., Mayne, Valerie, Simm, Peter J., Jones, Bryn O., Eggers, Stefanie, Le Guyader, Gwenaël, Pelluard, Fanny, Haack, Tobias B., Sturm, Marc, Riess, Angelika, Waldmueller, Stephan, Hofbeck, Michael, Steindl, Katharina, Joset, Pascal, Rauch, Anita, Hakonarson, Hakon, Baker, Naomi L., Farlie, Peter G.
Publicado no Am J Hum Genet (2017)