Dynamics of Resistance Development to Imatinib under Increasing Selection Pressure: A Combination of Mathematical Models and In Vitro Data

Por Werner, Benjamin, Lutz, David, Brümmendorf, Tim H., Traulsen, Arne, Balabanov, Stefan
Publicado em 2011

Epigenetic dysregulation of secreted frizzled-related proteins in myeloproliferative neoplasms complements the JAK2V617F-mutation

Por Bennemann Karla, Galm Oliver, Wilop Stefan, Schubert Claudia, Brümmendorf Tim H, Jost Edgar
Publicado em 2012-08-01

Aberrant DNA hypermethylation of the ITIH5 tumor suppressor gene in acute myeloid leukemia

Por Oing, Christoph, Jost, Edgar, Dahl, Edgar, Wilop, Stefan, Brümmendorf, Tim H., Galm, Oliver
Publicado em 2011

Epigenetic dysregulation of secreted frizzled-related proteins in myeloproliferative neoplasms complements the JAK2V617F-mutation

Por Bennemann, Karla, Galm, Oliver, Wilop, Stefan, Schubert, Claudia, Brümmendorf, Tim H, Jost, Edgar
Publicado em 2012

Asymmetric Cell Divisions Sustain Long-Term Hematopoiesis from Single-sorted Human Fetal Liver Cells

Por Brummendorf, Tim H., Dragowska, Wieslawa, Zijlmans, J.Mark J.M., Thornbury, Gayle, Lansdorp, Peter M.
Publicado em 1998

MicroRNA expression profiles of serum from patients before and after chemotherapy

Por Diener, Yvonne, Walenda, Thomas, Jost, Edgar, Brümmendorf, Tim H., Bosio, Andreas, Wagner, Wolfgang, Bissels, Ute
Publicado no Genom Data (2015)

Perioperative intravenous immunoglobulin treatment in a patient with severe acquired von Willebrand syndrome: case report and review of the literature

Por Jennes, Eva, Guggenberger, Dorothee, Zotz, Rainer, Thompson, Lora, Brümmendorf, Tim H., Koschmieder, Steffen, Jost, Edgar
Publicado no Clin Case Rep (2017)

Calreticulin-mutant proteins induce megakaryocytic signaling to transform hematopoietic cells and undergo accelerated degradation and Golgi-mediated secretion

Por Han, Lijuan, Schubert, Claudia, Köhler, Johanna, Schemionek, Mirle, Isfort, Susanne, Brümmendorf, Tim H., Koschmieder, Steffen, Chatain, Nicolas
Publicado no J Hematol Oncol (2016)

Telomere Fluorescence Measurements in Granulocytes and T Lymphocyte Subsets Point to a High Turnover of Hematopoietic Stem Cells and Memory T Cells in Early Childhood

Por Rufer, Nathalie, Brümmendorf, Tim H., Kolvraa, Steen, Bischoff, Claus, Christensen, Kaare, Wadsworth, Louis, Schulzer, Michael, Lansdorp, Peter M.
Publicado em 1999

Multi tyrosine kinase inhibitor dasatinib as novel cause of severe pre-capillary pulmonary hypertension?

Por Hennigs, Jan K, Keller, Gunhild, Baumann, Hans Jörg, Honecker, Friedemann, Kluge, Stefan, Bokemeyer, Carsten, Brümmendorf, Tim H, Klose, Hans
Publicado em 2011

Reconstructing the in vivo dynamics of hematopoietic stem cells from telomere length distributions

Por Werner, Benjamin, Beier, Fabian, Hummel, Sebastian, Balabanov, Stefan, Lassay, Lisa, Orlikowsky, Thorsten, Dingli, David, Brümmendorf, Tim H, Traulsen, Arne
Publicado no eLife (2015)

Combined Population Dynamics and Entropy Modelling Supports Patient Stratification in Chronic Myeloid Leukemia

Por Brehme, Marc, Koschmieder, Steffen, Montazeri, Maryam, Copland, Mhairi, Oehler, Vivian G., Radich, Jerald P., Brümmendorf, Tim H., Schuppert, Andreas
Publicado no Sci Rep (2016)

DNA-methylation in C1R is a prognostic biomarker for acute myeloid leukemia

Por Božić, Tanja, Lin, Qiong, Frobel, Joana, Wilop, Stefan, Hoffmann, Melanie, Müller-Tidow, Carsten, Brümmendorf, Tim H., Jost, Edgar, Wagner, Wolfgang
Publicado no Clin Epigenetics (2015)

Development of a disease-specific quality of life questionnaire for patients with aplastic anemia and/or paroxysmal nocturnal hemoglobinuria (QLQ-AA/PNH)—report on phases I and II...

Por Groth, Martha, Singer, Susanne, Niedeggen, Cathrin, Petermann-Meyer, Andrea, Röth, Alexander, Schrezenmeier, Hubert, Höchsmann, Britta, Brümmendorf, Tim H., Panse, Jens
Publicado no Ann Hematol (2016)

The SCLtTAxBCR-ABL transgenic mouse model closely reflects the differential effects of dasatinib on normal and malignant hematopoiesis in chronic phase-CML patients

Por Schubert, Claudia, Chatain, Nicolas, Braunschweig, Till, Schemionek, Mirle, Feldberg, Kristina, Hoffmann, Melanie, Dufva, Olli, Mustjoki, Satu, Brümmendorf, Tim H., Koschmieder, Steffen
Publicado no Oncotarget (2017)

Serum after Autologous Transplantation Stimulates Proliferation and Expansion of Human Hematopoietic Progenitor Cells

Por Walenda, Thomas, Bokermann, Gudrun, Jost, Edgar, Galm, Oliver, Schellenberg, Anne, Koch, Carmen M., Piroth, Daniela M., Drescher, Wolf, Brümmendorf, Tim H., Wagner, Wolfgang
Publicado em 2011

MicroRNAs and Metabolites in Serum Change after Chemotherapy: Impact on Hematopoietic Stem and Progenitor Cells

Por Walenda, Thomas, Diener, Yvonne, Jost, Edgar, Morin-Kensicki, Elizabeth, Goecke, Tamme W., Bosio, Andreas, Rath, Björn, Brümmendorf, Tim H., Bissels, Ute, Wagner, Wolfgang
Publicado no PLoS One (2015)

Aurora Kinase Inhibitor PHA-739358 Suppresses Growth of Hepatocellular Carcinoma In Vitro and in a Xenograft Mouse Model

Por Benten, Daniel, Keller, Gunhild, Quaas, Alexander, Schrader, Jorg, Gontarewicz, Artur, Balabanov, Stefan, Braig, Melanie, Wege, Henning, Moll, Jurgen, Lohse, Ansgar W, Brummendorf, Tim H
Publicado em 2009

Bosutinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukaemia: results from the 24-month follow-up of the BELA trial

Por Brümmendorf, Tim H, Cortes, Jorge E, de Souza, Cármino Antonio, Guilhot, Francois, Duvillié, Ladan, Pavlov, Dmitri, Gogat, Karïn, Countouriotis, Athena M, Gambacorti-Passerini, Carlo
Publicado no Br J Haematol (2015)

Combination of a Proteomics Approach and Reengineering of Meso Scale Network Models for Prediction of Mode-of-Action for Tyrosine Kinase Inhibitors

Por Balabanov, Stefan, Wilhelm, Thomas, Venz, Simone, Keller, Gunhild, Scharf, Christian, Pospisil, Heike, Braig, Melanie, Barett, Christine, Bokemeyer, Carsten, Walther, Reinhard, Brümmendorf, Tim H., Schuppert, Andreas
Publicado em 2013