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Reconstructing the in vivo dynamics of hematopoietic stem cells from telomere length distributions

We investigate the in vivo patterns of stem cell divisions in the human hematopoietic system throughout life. In particular, we analyze the shape of telomere length distributions underlying stem cell behavior within individuals. Our mathematical model shows that these distributions contain a fingerp...

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Foilsithe in:eLife
Main Authors: Werner, Benjamin, Beier, Fabian, Hummel, Sebastian, Balabanov, Stefan, Lassay, Lisa, Orlikowsky, Thorsten, Dingli, David, Brümmendorf, Tim H, Traulsen, Arne
Formáid: Artigo
Teanga:Inglês
Foilsithe: eLife Sciences Publications, Ltd 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744200/
https://ncbi.nlm.nih.gov/pubmed/26468615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08687
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