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Reconstructing the in vivo dynamics of hematopoietic stem cells from telomere length distributions
We investigate the in vivo patterns of stem cell divisions in the human hematopoietic system throughout life. In particular, we analyze the shape of telomere length distributions underlying stem cell behavior within individuals. Our mathematical model shows that these distributions contain a fingerp...
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| Publicado en: | eLife |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
eLife Sciences Publications, Ltd
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4744200/ https://ncbi.nlm.nih.gov/pubmed/26468615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08687 |
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