Reconstructing the in vivo dynamics of hematopoietic stem cells from telomere length distributions

We investigate the in vivo patterns of stem cell divisions in the human hematopoietic system throughout life. In particular, we analyze the shape of telomere length distributions underlying stem cell behavior within individuals. Our mathematical model shows that these distributions contain a fingerp...

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Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Werner, Benjamin, Beier, Fabian, Hummel, Sebastian, Balabanov, Stefan, Lassay, Lisa, Orlikowsky, Thorsten, Dingli, David, Brümmendorf, Tim H, Traulsen, Arne
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2015
Konular:
Computational and Systems Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744200/
https://ncbi.nlm.nih.gov/pubmed/26468615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08687
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