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Aurora Kinase Inhibitor PHA-739358 Suppresses Growth of Hepatocellular Carcinoma In Vitro and in a Xenograft Mouse Model

Patients with advanced stages of hepatocellular carcinoma (HCC) face a poor prognosis. Although encouraging clinical results have been obtained with multikinase inhibitor sorafenib, the development of improved therapeutic strategies for HCC remains an urgent goal. Aurora kinases are key regulators o...

詳細記述

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書誌詳細
主要な著者: Benten, Daniel, Keller, Gunhild, Quaas, Alexander, Schrader, Jorg, Gontarewicz, Artur, Balabanov, Stefan, Braig, Melanie, Wege, Henning, Moll, Jurgen, Lohse, Ansgar W, Brummendorf, Tim H
フォーマット: Artigo
言語:Inglês
出版事項: Neoplasia Press Inc. 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735802/
https://ncbi.nlm.nih.gov/pubmed/19724687
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