Aurora Kinase Inhibitor PHA-739358 Suppresses Growth of Hepatocellular Carcinoma In Vitro and in a Xenograft Mouse Model

Patients with advanced stages of hepatocellular carcinoma (HCC) face a poor prognosis. Although encouraging clinical results have been obtained with multikinase inhibitor sorafenib, the development of improved therapeutic strategies for HCC remains an urgent goal. Aurora kinases are key regulators o...

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Bibliographische Detailangaben
Hauptverfasser: Benten, Daniel, Keller, Gunhild, Quaas, Alexander, Schrader, Jorg, Gontarewicz, Artur, Balabanov, Stefan, Braig, Melanie, Wege, Henning, Moll, Jurgen, Lohse, Ansgar W, Brummendorf, Tim H
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press Inc. 2009
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735802/
https://ncbi.nlm.nih.gov/pubmed/19724687
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