Aurora Kinase Inhibitor PHA-739358 Suppresses Growth of Hepatocellular Carcinoma In Vitro and in a Xenograft Mouse Model

Patients with advanced stages of hepatocellular carcinoma (HCC) face a poor prognosis. Although encouraging clinical results have been obtained with multikinase inhibitor sorafenib, the development of improved therapeutic strategies for HCC remains an urgent goal. Aurora kinases are key regulators o...

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Detaylı Bibliyografya
Asıl Yazarlar: Benten, Daniel, Keller, Gunhild, Quaas, Alexander, Schrader, Jorg, Gontarewicz, Artur, Balabanov, Stefan, Braig, Melanie, Wege, Henning, Moll, Jurgen, Lohse, Ansgar W, Brummendorf, Tim H
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Neoplasia Press Inc. 2009
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735802/
https://ncbi.nlm.nih.gov/pubmed/19724687
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