Multi tyrosine kinase inhibitor dasatinib as novel cause of severe pre-capillary pulmonary hypertension?

BACKGROUND: Pulmonary hypertension (PH) is a life-threatening disease with poor prognosis. Encouraging efforts have been made to target the main vasoproliferative aspects of the disease. Promising emerging therapeutics are tyrosine kinase inhibitors such as imatinib. CASE PRESENTATION: Here, we disc...

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Autori principali: Hennigs, Jan K, Keller, Gunhild, Baumann, Hans Jörg, Honecker, Friedemann, Kluge, Stefan, Bokemeyer, Carsten, Brümmendorf, Tim H, Klose, Hans
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
Soggetti:
Case Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121732/
https://ncbi.nlm.nih.gov/pubmed/21605451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2466-11-30
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