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Subcellular Compartmentalization of Survivin is Associated with Biological Aggressiveness and Prognosis in Prostate Cancer

The role of subcellular survivin compartmentalization in the biology and prognosis of prostate cancer is unclear. We therefore investigated subcellular localization of survivin in more than 3000 prostate cancer patients by quantitative immunohistochemistry and performed transcriptomics of 250 prosta...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hennigs, Jan K., Minner, Sarah, Tennstedt, Pierre, Löser, Rolf, Huland, Hartwig, Klose, Hans, Graefen, Markus, Schlomm, Thorsten, Sauter, Guido, Bokemeyer, Carsten, Honecker, Friedemann
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039909/
https://ncbi.nlm.nih.gov/pubmed/32094363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60064-9
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