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Subcellular Compartmentalization of Survivin is Associated with Biological Aggressiveness and Prognosis in Prostate Cancer

The role of subcellular survivin compartmentalization in the biology and prognosis of prostate cancer is unclear. We therefore investigated subcellular localization of survivin in more than 3000 prostate cancer patients by quantitative immunohistochemistry and performed transcriptomics of 250 prosta...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Hennigs, Jan K., Minner, Sarah, Tennstedt, Pierre, Löser, Rolf, Huland, Hartwig, Klose, Hans, Graefen, Markus, Schlomm, Thorsten, Sauter, Guido, Bokemeyer, Carsten, Honecker, Friedemann
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039909/
https://ncbi.nlm.nih.gov/pubmed/32094363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60064-9
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