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Aberrant DNA hypermethylation of the ITIH5 tumor suppressor gene in acute myeloid leukemia
Epigenetic mechanisms such as DNA hypermethylation and modifications of histone amino acids are known to play an important role in the control of gene expression both in normal human development and tumorigenesis. Hypermethylation of CpG islands within promoter regions of tumor suppressor genes is a...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer-Verlag
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3365397/ https://ncbi.nlm.nih.gov/pubmed/22704354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13148-011-0043-5 |
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