Particle MCMC algorithms and architectures for accelerating inference in state-space models()

ανά Mingas, Grigorios, Bottolo, Leonardo, Bouganis, Christos-Savvas
Τόπος έκδοσης Int J Approx Reason (2017)

WGBSSuite: simulating whole-genome bisulphite sequencing data and benchmarking differential DNA methylation analysis tools

ανά Rackham, Owen J. L., Dellaportas, Petros, Petretto, Enrico, Bottolo, Leonardo
Τόπος έκδοσης Bioinformatics (2015)

Multi-tissue Analysis of Co-expression Networks by Higher-Order Generalized Singular Value Decomposition Identifies Functionally Coherent Transcriptional Modules

ανά Xiao, Xiaolin, Moreno-Moral, Aida, Rotival, Maxime, Bottolo, Leonardo, Petretto, Enrico
Έκδοση 2014

R2GUESS: A Graphics Processing Unit-Based R Package for Bayesian Variable Selection Regression of Multivariate Responses

ανά Liquet, Benoît, Bottolo, Leonardo, Campanella, Gianluca, Richardson, Sylvia, Chadeau-Hyam, Marc
Τόπος έκδοσης J Stat Softw (2016)

The chromosome 6q22.33 region is associated with age at diagnosis of type 1 diabetes and disease risk in those diagnosed under 5 years of age

ανά Inshaw, Jamie R. J., Walker, Neil M., Wallace, Chris, Bottolo, Leonardo, Todd, John A.
Τόπος έκδοσης Diabetologia (2017)

A computationally efficient Bayesian seemingly unrelated regressions model for high-dimensional quantitative trait loci discovery

ανά Bottolo, Leonardo, Banterle, Marco, Richardson, Sylvia, Ala-Korpela, Mika, Järvelin, Marjo-Riitta, Lewin, Alex
Τόπος έκδοσης J R Stat Soc Ser C Appl Stat (2021)

Bayesian Detection of Expression Quantitative Trait Loci Hot Spots

ανά Bottolo, Leonardo, Petretto, Enrico, Blankenberg, Stefan, Cambien, François, Cook, Stuart A., Tiret, Laurence, Richardson, Sylvia
Έκδοση 2011

EPISPOT: An epigenome-driven approach for detecting and interpreting hotspots in molecular QTL studies

ανά Ruffieux, Hélène, Fairfax, Benjamin P., Nassiri, Isar, Vigorito, Elena, Wallace, Chris, Richardson, Sylvia, Bottolo, Leonardo
Τόπος έκδοσης Am J Hum Genet (2021)

High-throughput multivariable Mendelian randomization analysis prioritizes apolipoprotein B as key lipid risk factor for coronary artery disease

ανά Zuber, Verena, Gill, Dipender, Ala-Korpela, Mika, Langenberg, Claudia, Butterworth, Adam, Bottolo, Leonardo, Burgess, Stephen
Τόπος έκδοσης Int J Epidemiol (2020)

A Global-Local Approach for Detecting Hotspots in Multiple-Response Regression

ανά Ruffieux, Hélène, Davison, Anthony C., Hager, Jörg, Inshaw, Jamie, Fairfax, Benjamin P., Richardson, Sylvia, Bottolo, Leonardo
Τόπος έκδοσης Ann Appl Stat (2020)

MethylCal: Bayesian calibration of methylation levels

ανά Ochoa, Eguzkine, Zuber, Verena, Fernandez-Jimenez, Nora, Bilbao, Jose Ramon, Clark, Graeme R, Maher, Eamonn R, Bottolo, Leonardo
Τόπος έκδοσης Nucleic Acids Res (2019)

ESS++: a C++ objected-oriented algorithm for Bayesian stochastic search model exploration

ανά Bottolo, Leonardo, Chadeau-Hyam, Marc, Hastie, David I., Langley, Sarah R., Petretto, Enrico, Tiret, Laurence, Tregouet, David, Richardson, Sylvia
Έκδοση 2011

Leveraging genetic data to elucidate the relationship between Covid-19 and ischemic stroke

ανά Zuber, Verena, Cameron, Alan, Myserlis, Evangelos P., Bottolo, Leonardo, Fernandez-Cadenas, Israel, Burgess, Stephen, Anderson, Christopher D., Dawson, Jesse, Gill, Dipender
Τόπος έκδοσης medRxiv (2021)

Systems-level approaches reveal conservation of trans-regulated genes in the rat and genetic determinants of blood pressure in humans

ανά Langley, Sarah R., Bottolo, Leonardo, Kunes, Jaroslav, Zicha, Josef, Zidek, Vaclav, Hubner, Norbert, Cook, Stuart A., Pravenec, Michal, Aitman, Timothy J., Petretto, Enrico
Έκδοση 2013

MT-HESS: an efficient Bayesian approach for simultaneous association detection in OMICS datasets, with application to eQTL mapping in multiple tissues

ανά Lewin, Alex, Saadi, Habib, Peters, James E., Moreno-Moral, Aida, Lee, James C., Smith, Kenneth G. C., Petretto, Enrico, Bottolo, Leonardo, Richardson, Sylvia
Τόπος έκδοσης Bioinformatics (2016)

Leptin-Mediated Changes in the Human Metabolome

ανά Lawler, Katherine, Huang-Doran, Isabel, Sonoyama, Takuhiro, Collet, Tinh-Hai, Keogh, Julia M, Henning, Elana, O’Rahilly, Stephen, Bottolo, Leonardo, Farooqi, I Sadaf
Τόπος έκδοσης J Clin Endocrinol Metab (2020)

A Bayesian Approach for Analysis of Whole-Genome Bisulfite Sequencing Data Identifies Disease-Associated Changes in DNA Methylation

ανά Rackham, Owen J. L., Langley, Sarah R., Oates, Thomas, Vradi, Eleni, Harmston, Nathan, Srivastava, Prashant K., Behmoaras, Jacques, Dellaportas, Petros, Bottolo, Leonardo, Petretto, Enrico
Τόπος έκδοσης Genetics (2017)

New Insights into the Genetic Control of Gene Expression using a Bayesian Multi-tissue Approach

ανά Petretto, Enrico, Bottolo, Leonardo, Langley, Sarah R., Heinig, Matthias, McDermott-Roe, Chris, Sarwar, Rizwan, Pravenec, Michal, Hübner, Norbert, Aitman, Timothy J., Cook, Stuart A., Richardson, Sylvia
Έκδοση 2010

Metabolic effects of bezafibrate in mitochondrial disease

ανά Steele, Hannah, Gomez‐Duran, Aurora, Pyle, Angela, Hopton, Sila, Newman, Jane, Stefanetti, Renae J, Charman, Sarah J, Parikh, Jehill D, He, Langping, Viscomi, Carlo, Jakovljevic, Djordje G, Hollingsworth, Kieren G, Robinson, Alan J, Taylor, Robert W, Bottolo, Leonardo, Horvath, Rita, Chinnery, Patrick F
Τόπος έκδοσης EMBO Mol Med (2020)

Prioritizing the Role of Major Lipoproteins and Subfractions as Risk Factors for Peripheral Artery Disease

ανά Levin, Michael G., Zuber, Verena, Walker, Venexia M., Klarin, Derek, Lynch, Julie, Malik, Rainer, Aday, Aaron W., Bottolo, Leonardo, Pradhan, Aruna D., Dichgans, Martin, Chang, Kyong-Mi, Rader, Daniel J., Tsao, Philip S., Voight, Benjamin F., Gill, Dipender, Burgess, Stephen, Damrauer, Scott M.
Τόπος έκδοσης Circulation (2021)