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A computationally efficient Bayesian seemingly unrelated regressions model for high-dimensional quantitative trait loci discovery

Our work is motivated by the search for metabolite quantitative trait loci (QTL) in a cohort of more than 5000 people. There are 158 metabolites measured by NMR spectroscopy in the 31-year follow-up of the Northern Finland Birth Cohort 1966 (NFBC66). These metabolites, as with many multivariate phen...

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Detalhes bibliográficos
Publicado no:J R Stat Soc Ser C Appl Stat
Main Authors: Bottolo, Leonardo, Banterle, Marco, Richardson, Sylvia, Ala-Korpela, Mika, Järvelin, Marjo-Riitta, Lewin, Alex
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612194/
https://ncbi.nlm.nih.gov/pubmed/35001978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/rssc.12490
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