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WGBSSuite: simulating whole-genome bisulphite sequencing data and benchmarking differential DNA methylation analysis tools

Motivation: As the number of studies looking at differences between DNA methylation increases, there is a growing demand to develop and benchmark statistical methods to analyse these data. To date no objective approach for the comparison of these methods has been developed and as such it remains dif...

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Dettagli Bibliografici
Pubblicato in:Bioinformatics
Autori principali: Rackham, Owen J. L., Dellaportas, Petros, Petretto, Enrico, Bottolo, Leonardo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495289/
https://ncbi.nlm.nih.gov/pubmed/25777524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv114
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