The combination of CHK1 inhibitor with G-CSF overrides cytarabine resistance in human acute myeloid leukemia

מאת Di Tullio, Alessandro, Rouault-Pierre, Kevin, Abarrategi, Ander, Mian, Syed, Grey, William, Gribben, John, Stewart, Aengus, Blackwood, Elizabeth, Bonnet, Dominique
הוצא לאור ב Nat Commun (2017)

The Nck-interacting kinase phosphorylates ERM proteins for formation of lamellipodium by growth factors

מאת Baumgartner, Martin, Sillman, Amy L., Blackwood, Elizabeth M., Srivastava, Jyoti, Madson, Nikki, Schilling, James W., Wright, Jocelyn H., Barber, Diane L.
יצא לאור 2006

Targeting p21-activated kinase 1 (PAK1) to induce apoptosis of tumor cells

מאת Ong, Christy C., Jubb, Adrian M., Haverty, Peter M., Zhou, Wei, Tran, Victoria, Truong, Tom, Turley, Helen, O'Brien, Tom, Vucic, Domagoj, Harris, Adrian L., Belvin, Marcia, Friedman, Lori S., Blackwood, Elizabeth M., Koeppen, Hartmut, Hoeflich, Klaus P.
יצא לאור 2011

Development of a Potent, Specific CDK8 Kinase Inhibitor Which Phenocopies CDK8/19 Knockout Cells

מאת Koehler, Michael F. T., Bergeron, Philippe, Blackwood, Elizabeth M., Bowman, Krista, Clark, Kevin R., Firestein, Ron, Kiefer, James R., Maskos, Klaus, McCleland, Mark L., Orren, Linda, Salphati, Laurent, Schmidt, Steve, Schneider, Elisabeth V., Wu, Jiansheng, Beresini, Maureen H.
הוצא לאור ב ACS Med Chem Lett (2016)

Design and Development of a Series of Potent and Selective Type II Inhibitors of CDK8

מאת Bergeron, Philippe, Koehler, Michael F. T., Blackwood, Elizabeth M., Bowman, Krista, Clark, Kevin, Firestein, Ron, Kiefer, James R., Maskos, Klaus, McCleland, Mark L., Orren, Linda, Ramaswamy, Sreemathy, Salphati, Laurent, Schmidt, Steve, Schneider, Elisabeth V., Wu, Jiansheng, Beresini, Maureen
הוצא לאור ב ACS Med Chem Lett (2016)

An integrative analysis of colon cancer identifies an essential function for PRPF6 in tumor growth

מאת Adler, Adam S., McCleland, Mark L., Yee, Sharon, Yaylaoglu, Murat, Hussain, Sofia, Cosino, Ely, Quinones, Gabriel, Modrusan, Zora, Seshagiri, Somasekar, Torres, Eric, Chopra, Vivek S., Haley, Benjamin, Zhang, Zemin, Blackwood, Elizabeth M., Singh, Mallika, Junttila, Melissa, Stephan, Jean-Philippe, Liu, Jinfeng, Pau, Gregoire, Fearon, Eric R., Jiang, Zhaoshi, Firestein, Ron
יצא לאור 2014

Discovery and Biological Profiling of Potent and Selective mTOR Inhibitor GDC-0349

מאת Pei, Zhonghua, Blackwood, Elizabeth, Liu, Lichuan, Malek, Shiva, Belvin, Marcia, Koehler, Michael F. T., Ortwine, Daniel F., Chen, Huifen, Cohen, Frederick, Kenny, Jane R., Bergeron, Philippe, Lau, Kevin, Ly, Cuong, Zhao, Xianrui, Estrada, Anthony A., Truong, Tom, Epler, Jennifer A., Nonomiya, Jim, Trinh, Lan, Sideris, Steve, Lesnick, John, Bao, Linda, Vijapurkar, Ulka, Mukadam, Sophie, Tay, Suzanne, Deshmukh, Gauri, Chen, Yung-Hsiang, Ding, Xiao, Friedman, Lori S., Lyssikatos, Joseph P.
יצא לאור 2012

Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-pK(a) Polar Moiety

מאת Ndubaku, Chudi O., Crawford, James J., Drobnick, Joy, Aliagas, Ignacio, Campbell, David, Dong, Ping, Dornan, Laura M., Duron, Sergio, Epler, Jennifer, Gazzard, Lewis, Heise, Christopher E., Hoeflich, Klaus P., Jakubiak, Diana, La, Hank, Lee, Wendy, Lin, Baiwei, Lyssikatos, Joseph P., Maksimoska, Jasna, Marmorstein, Ronen, Murray, Lesley J., O’Brien, Thomas, Oh, Angela, Ramaswamy, Sreemathy, Wang, Weiru, Zhao, Xianrui, Zhong, Yu, Blackwood, Elizabeth, Rudolph, Joachim
הוצא לאור ב ACS Med Chem Lett (2015)