Modeling human disease in rodents by CRISPR/Cas9 genome editing

מאת Birling, Marie-Christine, Herault, Yann, Pavlovic, Guillaume
הוצא לאור ב Mamm Genome (2017)

Targeting the RHOA pathway improves learning and memory in adult Kctd13 and 16p11.2 deletion mouse models

מאת Martin Lorenzo, Sandra, Nalesso, Valérie, Chevalier, Claire, Birling, Marie-Christine, Herault, Yann
הוצא לאור ב Mol Autism (2021)

Severe head dysgenesis resulting from imbalance between anterior and posterior ontogenetic programs

מאת Grall, Emmanuelle, Gourain, Victor, Naïr, Asmaa, Martin, Elisabeth, Birling, Marie-Christine, Freund, Jean-Noël, Duluc, Isabelle
הוצא לאור ב Cell Death Dis (2019)

Targeted deletion of kidney glucose-6 phosphatase leads to nephropathy

מאת clar, julie, Gri, Blandine, Calderaro, Julien, Birling, Marie-Christine, Herault, Yann, Smith, Peter, Mithieux, Gilles, Rajas, Fabienne
הוצא לאור ב Kidney Int (2014)

Efficient and rapid generation of large genomic variants in rats and mice using CRISMERE

מאת Birling, Marie-Christine, Schaeffer, Laurence, André, Philippe, Lindner, Loic, Maréchal, Damien, Ayadi, Abdel, Sorg, Tania, Pavlovic, Guillaume, Hérault, Yann
הוצא לאור ב Sci Rep (2017)

The neuroanatomy of Eml1 knockout mice, a model of subcortical heterotopia

מאת Collins, Stephan C., Uzquiano, Ana, Selloum, Mohammed, Wendling, Olivia, Gaborit, Marion, Osipenko, Maria, Birling, Marie‐Christine, Yalcin, Binnaz, Francis, Fiona
הוצא לאור ב J Anat (2019)

Rfx6 Maintains the Functional Identity of Adult Pancreatic β Cells

מאת Piccand, Julie, Strasser, Perrine, Hodson, David J., Meunier, Aline, Ye, Tao, Keime, Céline, Birling, Marie-Christine, Rutter, Guy A., Gradwohl, Gérard
הוצא לאור ב Cell Rep (2014)

Transgenic mouse models expressing human and macaque prion protein exhibit similar prion susceptibility on a strain-dependent manner

מאת Espinosa, Juan Carlos, Comoy, Emmanuel E., Marin-Moreno, Alba, Aguilar-Calvo, Patricia, Birling, Marie-Christine, Pitarch, José Luis, Deslys, Jean-Philippe, Torres, Juan María
הוצא לאור ב Sci Rep (2019)

Reciprocal Effects on Neurocognitive and Metabolic Phenotypes in Mouse Models of 16p11.2 Deletion and Duplication Syndromes

מאת Arbogast, Thomas, Ouagazzal, Abdel-Mouttalib, Chevalier, Claire, Kopanitsa, Maksym, Afinowi, Nurudeen, Migliavacca, Eugenia, Cowling, Belinda S., Birling, Marie-Christine, Champy, Marie-France, Reymond, Alexandre, Herault, Yann
הוצא לאור ב PLoS Genet (2016)

Targeting Morphine-Responsive Neurons: Generation of a Knock-In Mouse Line Expressing Cre Recombinase from the Mu-Opioid Receptor Gene Locus

מאת Bailly, Julie, Del Rossi, Natalie, Runtz, Léonie, Li, Jing-Jing, Park, DaWoon, Scherrer, Grégory, Tanti, Arnaud, Birling, Marie-Christine, Darcq, Emmanuel, Kieffer, Brigitte L.
הוצא לאור ב eNeuro (2020)

Repression of Osteoblast Maturation by ERRα Accounts for Bone Loss Induced by Estrogen Deficiency

מאת Gallet, Marlène, Saïdi, Soraya, Haÿ, Eric, Photsavang, Johann, Marty, Caroline, Sailland, Juliette, Carnesecchi, Julie, Tribollet, Violaine, Barenton, Bruno, Forcet, Christelle, Birling, Marie-Christine, Sorg, Tania, Chassande, Olivier, Cohen-Solal, Martine, Vanacker, Jean-Marc
יצא לאור 2013

A mu–delta opioid receptor brain atlas reveals neuronal co-occurrence in subcortical networks

מאת Erbs, Eric, Faget, Lauren, Scherrer, Gregory, Matifas, Audrey, Filliol, Dominique, Vonesch, Jean-Luc, Koch, Marc, Kessler, Pascal, Hentsch, Didier, Birling, Marie-Christine, Koutsourakis, Manoussos, Vasseur, Laurent, Veinante, Pierre, Kieffer, Brigitte L., Massotte, Dominique
הוצא לאור ב Brain Struct Funct (2014)

Aneuploidy screening of embryonic stem cell clones by metaphase karyotyping and droplet digital polymerase chain reaction

מאת Codner, Gemma F., Lindner, Loic, Caulder, Adam, Wattenhofer-Donzé, Marie, Radage, Adam, Mertz, Annelyse, Eisenmann, Benjamin, Mianné, Joffrey, Evans, Edward P., Beechey, Colin V., Fray, Martin D., Birling, Marie-Christine, Hérault, Yann, Pavlovic, Guillaume, Teboul, Lydia
הוצא לאור ב BMC Cell Biol (2016)

A new mouse model of ARX dup24 recapitulates the patients’ behavioral and fine motor alterations

מאת Dubos, Aline, Meziane, Hamid, Iacono, Giovanni, Curie, Aurore, Riet, Fabrice, Martin, Christelle, Loaëc, Nadège, Birling, Marie-Christine, Selloum, Mohammed, Normand, Elisabeth, Pavlovic, Guillaume, Sorg, Tania, Stunnenberg, Henk G, Chelly, Jamel, Humeau, Yann, Friocourt, Gaëlle, Hérault, Yann
הוצא לאור ב Hum Mol Genet (2018)

Hyperactivation of Alk induces neonatal lethality in knock-in Alk(F1178L) mice

מאת Lopez-Delisle, Lucille, Pierre-Eugène, Cécile, Bloch-Gallego, Evelyne, Birling, Marie-Christine, Duband, Jean-Loup, Durand, Estelle, Bourgeois, Thomas, Matrot, Boris, Sorg, Tania, Huerre, Michel, Meziane, Hamid, Roux, Michel J., Champy, Marie-France, Gallego, Jorge, Delattre, Olivier, Janoueix-Lerosey, Isabelle
יצא לאור 2014

Absence of TI-VAMP/Vamp7 Leads to Increased Anxiety in Mice

מאת Danglot, Lydia, Zylbersztejn, Kathleen, Petkovic, Maja, Gauberti, Maxime, Meziane, Hamid, Combe, Roy, Champy, Marie-France, Birling, Marie-Christine, Pavlovic, Guillaume, Bizot, Jean-Charles, Trovero, Fabrice, Della Ragione, Floriana, Proux-Gillardeaux, Véronique, Sorg, Tania, Vivien, Denis, D'Esposito, Maurizio, Galli, Thierry
הוצא לאור ב J Neurosci (2012)

Conditional switching of KIF2A mutation provides new insights into cortical malformation pathogeny

מאת Gilet, Johan G, Ivanova, Ekaterina L, Trofimova, Daria, Rudolf, Gabrielle, Meziane, Hamid, Broix, Loic, Drouot, Nathalie, Courraud, Jeremie, Skory, Valerie, Voulleminot, Paul, Osipenko, Maria, Bahi-Buisson, Nadia, Yalcin, Binnaz, Birling, Marie-Christine, Hinckelmann, Maria-Victoria, Kwok, Benjamin H, Allingham, John S, Chelly, Jamel
הוצא לאור ב Hum Mol Genet (2020)

The cell proliferation antigen Ki-67 organises heterochromatin

מאת Sobecki, Michal, Mrouj, Karim, Camasses, Alain, Parisis, Nikolaos, Nicolas, Emilien, Llères, David, Gerbe, François, Prieto, Susana, Krasinska, Liliana, David, Alexandre, Eguren, Manuel, Birling, Marie-Christine, Urbach, Serge, Hem, Sonia, Déjardin, Jérôme, Malumbres, Marcos, Jay, Philippe, Dulic, Vjekoslav, Lafontaine, Denis LJ, Feil, Robert, Fisher, Daniel
הוצא לאור ב eLife (2016)

Conditional depletion of intellectual disability and Parkinsonism candidate gene ATP6AP2 in fly and mouse induces cognitive impairment and neurodegeneration

מאת Dubos, Aline, Castells-Nobau, Anna, Meziane, Hamid, Oortveld, Merel A.W., Houbaert, Xander, Iacono, Giovanni, Martin, Christelle, Mittelhaeuser, Christophe, Lalanne, Valérie, Kramer, Jamie M., Bhukel, Anuradha, Quentin, Christine, Slabbert, Jan, Verstreken, Patrik, Sigrist, Stefan J., Messaddeq, Nadia, Birling, Marie-Christine, Selloum, Mohammed, Stunnenberg, Henk G., Humeau, Yann, Schenck, Annette, Herault, Yann
הוצא לאור ב Hum Mol Genet (2015)

Mouse models of 17q21.31 microdeletion and microduplication syndromes highlight the importance of Kansl1 for cognition

מאת Arbogast, Thomas, Iacono, Giovanni, Chevalier, Claire, Afinowi, Nurudeen O., Houbaert, Xander, van Eede, Matthijs C., Laliberte, Christine, Birling, Marie-Christine, Linda, Katrin, Meziane, Hamid, Selloum, Mohammed, Sorg, Tania, Nadif Kasri, Nael, Koolen, David A., Stunnenberg, Henk G., Henkelman, R. Mark, Kopanitsa, Maksym, Humeau, Yann, De Vries, Bert B. A., Herault, Yann
הוצא לאור ב PLoS Genet (2017)