Targeting the RHOA pathway improves learning and memory in adult Kctd13 and 16p11.2 deletion mouse models

BACKGROUND: Gene copy number variants play an important role in the occurrence of neurodevelopmental disorders. Particularly, the deletion of the 16p11.2 locus is associated with autism spectrum disorder, intellectual disability, and several other features. Earlier studies highlighted the implicatio...

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Veröffentlicht in:Mol Autism
Hauptverfasser: Martin Lorenzo, Sandra, Nalesso, Valérie, Chevalier, Claire, Birling, Marie-Christine, Herault, Yann
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7805198/
https://ncbi.nlm.nih.gov/pubmed/33436060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13229-020-00405-7
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