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Targeting the RHOA pathway improves learning and memory in adult Kctd13 and 16p11.2 deletion mouse models

BACKGROUND: Gene copy number variants play an important role in the occurrence of neurodevelopmental disorders. Particularly, the deletion of the 16p11.2 locus is associated with autism spectrum disorder, intellectual disability, and several other features. Earlier studies highlighted the implicatio...

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發表在:Mol Autism
Main Authors: Martin Lorenzo, Sandra, Nalesso, Valérie, Chevalier, Claire, Birling, Marie-Christine, Herault, Yann
格式: Artigo
語言:Inglês
出版: BioMed Central 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7805198/
https://ncbi.nlm.nih.gov/pubmed/33436060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13229-020-00405-7
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