Reciprocal Effects on Neurocognitive and Metabolic Phenotypes in Mouse Models of 16p11.2 Deletion and Duplication Syndromes

The 16p11.2 600 kb BP4-BP5 deletion and duplication syndromes have been associated with developmental delay; autism spectrum disorders; and reciprocal effects on the body mass index, head circumference and brain volumes. Here, we explored these relationships using novel engineered mouse models carry...

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Publicat a:PLoS Genet
Autors principals: Arbogast, Thomas, Ouagazzal, Abdel-Mouttalib, Chevalier, Claire, Kopanitsa, Maksym, Afinowi, Nurudeen, Migliavacca, Eugenia, Cowling, Belinda S., Birling, Marie-Christine, Champy, Marie-France, Reymond, Alexandre, Herault, Yann
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752317/
https://ncbi.nlm.nih.gov/pubmed/26872257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005709
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