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Rfx6 Maintains the Functional Identity of Adult Pancreatic β Cells
Increasing evidence suggests that loss of β cell characteristics may cause insulin secretory deficiency in diabetes, but the underlying mechanisms remain unclear. Here, we show that Rfx6, whose mutation leads to neonatal diabetes in humans, is essential to maintain key features of functionally matur...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4542305/ https://ncbi.nlm.nih.gov/pubmed/25497096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.11.033 |
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