Rfx6 Maintains the Functional Identity of Adult Pancreatic β Cells

Increasing evidence suggests that loss of β cell characteristics may cause insulin secretory deficiency in diabetes, but the underlying mechanisms remain unclear. Here, we show that Rfx6, whose mutation leads to neonatal diabetes in humans, is essential to maintain key features of functionally matur...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Piccand, Julie, Strasser, Perrine, Hodson, David J., Meunier, Aline, Ye, Tao, Keime, Céline, Birling, Marie-Christine, Rutter, Guy A., Gradwohl, Gérard
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542305/
https://ncbi.nlm.nih.gov/pubmed/25497096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.11.033
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker