Pathogenic yeasts

door Ashbee, Ruth., Bignell, Elaine M.
Gepubliceerd in 2010

Transcript levels of the Aspergillus fumigatus Cdc42 module, polarisome, and septin genes show little change from dormancy to polarity establishment

door Oda, Ken, Bignell, Elaine, Kang, S. Earl, Momany, Michelle
Gepubliceerd in Med Mycol (2017)

Microbial uptake by the respiratory epithelium: outcomes for host and pathogen

door Bertuzzi, Margherita, Hayes, Gemma E, Bignell, Elaine M
Gepubliceerd in FEMS Microbiol Rev (2019)

A Regulator of Aspergillus fumigatus Extracellular Proteolytic Activity Is Dispensable for Virulence

door Bergmann, Anna, Hartmann, Thomas, Cairns, Timothy, Bignell, Elaine M., Krappmann, Sven
Gepubliceerd in 2009

Developing novel antifungals: lessons from G protein-coupled receptors

door Velazhahan, Vaithish, McCann, Bethany L., Bignell, Elaine, Tate, Christopher G.
Gepubliceerd in Trends Pharmacol Sci (2023)

Secondary metabolite arsenal of an opportunistic pathogenic fungus

door Bignell, Elaine, Cairns, Timothy C., Throckmorton, Kurt, Nierman, William C., Keller, Nancy P.
Gepubliceerd in Philos Trans R Soc Lond B Biol Sci (2016)

Different Stress-Induced Calcium Signatures Are Reported by Aequorin-Mediated Calcium Measurements in Living Cells of Aspergillus fumigatus

door Muñoz, Alberto, Bertuzzi, Margherita, Bettgenhaeuser, Jan, Iakobachvili, Nino, Bignell, Elaine M., Read, Nick D.
Gepubliceerd in PLoS One (2015)

Virulence Comparisons of Aspergillus nidulans Mutants Are Confounded by the Inflammatory Response of p47(phox)(−/−) Mice

door Bignell, Elaine, Negrete-Urtasun, Susana, Calcagno, Ana Maria, Arst, Herbert N., Rogers, Tom, Haynes, Ken
Gepubliceerd in 2005

On the lineage of Aspergillus fumigatus isolates in common laboratory use

door Bertuzzi, Margherita, van Rhijn, Norman, Krappmann, Sven, Bowyer, Paul, Bromley, Michael J, Bignell, Elaine M
Gepubliceerd in Med Mycol (2020)

Development of a marker-free mutagenesis system using CRISPR-Cas9 in the pathogenic mould Aspergillus fumigatus

door van Rhijn, Norman, Furukawa, Takanori, Zhao, Can, McCann, Bethany L., Bignell, Elaine, Bromley, Michael J.
Gepubliceerd in Fungal Genet Biol (2020)

Siderophore Biosynthesis But Not Reductive Iron Assimilation Is Essential for Aspergillus fumigatus Virulence

door Schrettl, Markus, Bignell, Elaine, Kragl, Claudia, Joechl, Chistoph, Rogers, Tom, Arst, Herbert N., Haynes, Ken, Haas, Hubertus
Gepubliceerd in 2004

In silico modeling of spore inhalation reveals fungal persistence following low dose exposure

door Tanaka, Reiko J., Boon, Neville J., Vrcelj, Katarina, Nguyen, Anita, Vinci, Carmelina, Armstrong-James, Darius, Bignell, Elaine
Gepubliceerd in Sci Rep (2015)

A new and clinically relevant murine model of solid-organ transplant aspergillosis

door Herbst, Susanne, Shah, Anand, Carby, Martin, Chusney, Gary, Kikkeri, Naresh, Dorling, Anthony, Bignell, Elaine, Shaunak, Sunil, Armstrong-James, Darius
Gepubliceerd in 2013

Anti-Aspergillus Activities of the Respiratory Epithelium in Health and Disease

door Bertuzzi, Margherita, Hayes, Gemma E., Icheoku, Uju J., van Rhijn, Norman, Denning, David W., Osherov, Nir, Bignell, Elaine M.
Gepubliceerd in J Fungi (Basel) (2018)

Mechanistic Basis of pH-Dependent 5-Flucytosine Resistance in Aspergillus fumigatus

door Gsaller, Fabio, Furukawa, Takanori, Carr, Paul D., Rash, Bharat, Jöchl, Christoph, Bertuzzi, Margherita, Bignell, Elaine M., Bromley, Michael J.
Gepubliceerd in Antimicrob Agents Chemother (2018)

A Modified Recombineering Protocol for the Genetic Manipulation of Gene Clusters in Aspergillus fumigatus

door Alcazar-Fuoli, Laura, Cairns, Timothy, Lopez, Jordi F., Zonja, Bozo, Pérez, Sandra, Barceló, Damià, Igarashi, Yasuhiro, Bowyer, Paul, Bignell, Elaine
Gepubliceerd in PLoS One (2014)

Distinct Roles for Intra- and Extracellular Siderophores during Aspergillus fumigatus Infection

door Schrettl, Markus, Bignell, Elaine, Kragl, Claudia, Sabiha, Yasmin, Loss, Omar, Eisendle, Martin, Wallner, Anja, Arst, Herbert N, Haynes, Ken, Haas, Hubertus
Gepubliceerd in 2007

Mevalonate governs interdependency of ergosterol and siderophore biosyntheses in the fungal pathogen Aspergillus fumigatus

door Yasmin, Sabiha, Alcazar-Fuoli, Laura, Gründlinger, Mario, Puempel, Thomas, Cairns, Timothy, Blatzer, Michael, Lopez, Jordi F., Grimalt, Joan O., Bignell, Elaine, Haas, Hubertus
Gepubliceerd in 2012

Genetic Bypass of Aspergillus nidulans crzA Function in Calcium Homeostasis

door Almeida, Ricardo S., Loss, Omar, Colabardini, Ana Cristina, Brown, Neil Andrew, Bignell, Elaine, Savoldi, Marcela, Pantano, Sergio, Goldman, Maria Helena S., Arst, Herbert N., Goldman, Gustavo H.
Gepubliceerd in 2013

On how a transcription factor can avoid its proteolytic activation in the absence of signal transduction

door Espeso, Eduardo A., Roncal, Tomás, Díez, Eliecer, Rainbow, Lynne, Bignell, Elaine, Álvaro, Josué, Suárez, Teresa, Denison, Steven H., Tilburn, Joan, Arst, Herbert N., Peñalva, Miguel A.
Gepubliceerd in 2000