Sweet and Sour β-Cells: ROS and Hif1α Induce Warburg-Like Lactate Production During Type 2 Diabetes

Por Cantley, James, Biden, Trevor J.
Publicado em 2013

Protein Kinase C Function in Muscle, Liver, and β-Cells and Its Therapeutic Implications for Type 2 Diabetes

Por Schmitz-Peiffer, Carsten, Biden, Trevor J.
Publicado em 2008

Bad News for β-Cell Apoptosis

Por Thomas, Helen E., Biden, Trevor J.
Publicado em 2009

PKCδ Blues for the β-Cell

Por Schmitz-Peiffer, Carsten, Biden, Trevor J.
Publicado em 2010

Roles of ceramide and sphingolipids in pancreatic β-cell function and dysfunction

Por Boslem, Ebru, Meikle, Peter J., Biden, Trevor J.
Publicado em 2012

Failure of the Adaptive Unfolded Protein Response in Islets of Obese Mice Is Linked With Abnormalities in β-Cell Gene Expression and Progression to Diabetes

Por Chan, Jeng Yie, Luzuriaga, Jude, Bensellam, Mohammed, Biden, Trevor J., Laybutt, D. Ross
Publicado em 2013

Deletion of PKCε Selectively Enhances the Amplifying Pathways of Glucose-Stimulated Insulin Secretion via Increased Lipolysis in Mouse β-Cells

Por Cantley, James, Burchfield, James G., Pearson, Gemma L., Schmitz-Peiffer, Carsten, Leitges, Michael, Biden, Trevor J.
Publicado em 2009

A comprehensive lipidomic screen of pancreatic β-cells using mass spectroscopy defines novel features of glucose-stimulated turnover of neutral lipids, sphingolipids and plasmaloge...

Por Pearson, Gemma L., Mellett, Natalie, Chu, Kwan Yi, Boslem, Ebru, Meikle, Peter J., Biden, Trevor J.
Publicado no Mol Metab (2016)

Alteration of Endoplasmic Reticulum Lipid Rafts Contributes to Lipotoxicity in Pancreatic β-Cells

Por Boslem, Ebru, Weir, Jacquelyn M., MacIntosh, Gemma, Sue, Nancy, Cantley, James, Meikle, Peter J., Biden, Trevor J.
Publicado em 2013

Identification of fatty acid binding protein 4 as an adipokine that regulates insulin secretion during obesity

Por Wu, Lindsay E., Samocha-Bonet, Dorit, Whitworth, P. Tess, Fazakerley, Daniel J., Turner, Nigel, Biden, Trevor J., James, David E., Cantley, James
Publicado em 2014

Cytokine-Induced β-Cell Death Is Independent of Endoplasmic Reticulum Stress Signaling

Por Åkerfeldt, Mia C., Howes, Jennifer, Chan, Jeng Yie, Stevens, Veronica A., Boubenna, Nacer, McGuire, Helen M., King, Cecile, Biden, Trevor J., Laybutt, D. Ross
Publicado em 2008

Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice

Por Cooney, Gregory J, Lyons, Ruth J, Crew, A Jayne, Jensen, Thomas E, Molero, Juan Carlos, Mitchell, Christopher J, Biden, Trevor J, Ormandy, Christopher J, James, David E, Daly, Roger J
Publicado em 2004

Glucose Homeostasis in Mice Is Transglutaminase 2 Independent

Por Iismaa, Siiri E., Aplin, Mark, Holman, Sara, Yiu, Ting W., Jackson, Kristy, Burchfield, James G., Mitchell, Christopher J., O’Reilly, Liam, Davenport, Aimee, Cantley, James, Schmitz-Peiffer, Carsten, Biden, Trevor J., Cooney, Gregory J., Graham, Robert M.
Publicado em 2013