Challenges for and current status of research into positive modulators of AMPA receptors

gan Ward, Simon E, Bax, Benjamin D, Harries, Mark
Cyhoeddwyd 2010

DNA Topoisomerase Inhibitors: Trapping a DNA-Cleaving Machine in Motion

gan Bax, Benjamin D., Murshudov, Garib, Maxwell, Anthony, Germe, Thomas
Cyhoeddwyd yn J Mol Biol (2019)

Conformational flexibility within the small domain of human serine racemase

gan Koulouris, Chloe R., Bax, Benjamin D., Atack, John R., Roe, S. Mark
Cyhoeddwyd yn Acta Crystallogr F Struct Biol Commun (2020)

Crystallization and structure of ebselen bound to Cys141 of human inositol monophosphatase

gan Fenn, Gareth D., Waller-Evans, Helen, Atack, John R., Bax, Benjamin D.
Cyhoeddwyd yn Acta Crystallogr F Struct Biol Commun (2020)

Purification, crystallization and preliminary X-ray crystallographic studies of the Mycobacterium tuberculosis DNA gyrase ATPase domain

gan Roué, Mélanie, Agrawal, Alka, Volker, Craig, Mossakowska, Danuta, Mayer, Claudine, Bax, Benjamin D.
Cyhoeddwyd 2013

A new class of antibacterials, the imidazopyrazinones, reveal structural transitions involved in DNA gyrase poisoning and mechanisms of resistance

gan Germe, Thomas, Vörös, Judit, Jeannot, Frederic, Taillier, Thomas, Stavenger, Robert A, Bacqué, Eric, Maxwell, Anthony, Bax, Benjamin D
Cyhoeddwyd yn Nucleic Acids Res (2018)

A new class of antibacterials, the imidazopyrazinones, reveal structural transitions involved in DNA gyrase poisoning and mechanisms of resistance

gan Germe, Thomas, Vörös, Judit, Jeannot, Frederic, Taillier, Thomas, Stavenger, Robert A, Bacqué, Eric, Maxwell, Anthony, Bax, Benjamin D
Cyhoeddwyd yn Nucleic Acids Res (2018)

From PIM1 to PI3Kδ via GSK3β: Target Hopping through the Kinome

gan Henley, Zoë A., Bax, Benjamin D., Inglesby, Laura M., Champigny, Aurélie, Gaines, Simon, Faulder, Paul, Le, Joelle, Thomas, Daniel A., Washio, Yoshiaki, Baldwin, Ian R.
Cyhoeddwyd yn ACS Med Chem Lett (2017)

Protein Arginine Deiminase 2 Binds Calcium in an Ordered Fashion: Implications for Inhibitor Design

gan Slade, Daniel J., Fang, Pengfei, Dreyton, Christina J., Zhang, Ying, Fuhrmann, Jakob, Rempel, Don, Bax, Benjamin D., Coonrod, Scott A., Lewis, Huw D., Guo, Min, Gross, Michael L., Thompson, Paul R.
Cyhoeddwyd yn ACS Chem Biol (2015)

Crystallization and initial crystallographic analysis of covalent DNA-cleavage complexes of Staphyloccocus aureus DNA gyrase with QPT-1, moxifloxacin and etoposide

gan Srikannathasan, Velupillai, Wohlkonig, Alexandre, Shillings, Anthony, Singh, Onkar, Chan, Pan F., Huang, Jianzhong, Gwynn, Michael N., Fosberry, Andrew P., Homes, Paul, Hibbs, Martin, Theobald, Andrew J., Spitzfaden, Claus, Bax, Benjamin D.
Cyhoeddwyd yn Acta Crystallogr F Struct Biol Commun (2015)

Crystallizing Membrane Proteins in the Lipidic Mesophase. Experience with Human Prostaglandin E2 Synthase 1 and an Evolving Strategy

gan Li, Dianfan, Howe, Nicole, Dukkipati, Abhiram, Shah, Syed T. A., Bax, Benjamin D., Edge, Colin, Bridges, Angela, Hardwicke, Phil, Singh, Onkar M. P., Giblin, Ged, Pautsch, Alexander, Pfau, Roland, Schnapp, Gisela, Wang, Meitian, Olieric, Vincent, Caffrey, Martin
Cyhoeddwyd 2014

Thiophene antibacterials that allosterically stabilize DNA-cleavage complexes with DNA gyrase

gan Chan, Pan F., Germe, Thomas, Bax, Benjamin D., Huang, Jianzhong, Thalji, Reema K., Bacqué, Eric, Checchia, Anna, Chen, Dongzhao, Cui, Haifeng, Ding, Xiao, Ingraham, Karen, McCloskey, Lynn, Raha, Kaushik, Srikannathasan, Velupillai, Maxwell, Anthony, Stavenger, Robert A.
Cyhoeddwyd yn Proc Natl Acad Sci U S A (2017)

Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin

gan Chan, Pan F., Srikannathasan, Velupillai, Huang, Jianzhong, Cui, Haifeng, Fosberry, Andrew P., Gu, Minghua, Hann, Michael M., Hibbs, Martin, Homes, Paul, Ingraham, Karen, Pizzollo, Jason, Shen, Carol, Shillings, Anthony J., Spitzfaden, Claus E., Tanner, Robert, Theobald, Andrew J., Stavenger, Robert A., Bax, Benjamin D., Gwynn, Michael N.
Cyhoeddwyd yn Nat Commun (2015)

Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation

gan Lewis, Huw D., Liddle, John, Coote, Jim E., Atkinson, Stephen J., Barker, Michael D., Bax, Benjamin, D., Bicker, Kevin L., Bingham, Ryan P., Campbell, Matthew, Chen, Yu Hua, Chung, Chun-wa, Craggs, Peter D., Davis, Rob P., Eberhard, Dirk, Joberty, Gerard, Lind, Kenneth E., Locke, Kelly, Maller, Claire, Martinod, Kimberly, Patten, Chris, Polyakova, Oxana, Rise, Cecil E., Rüdiger, Martin, Sheppard, Robert J., Slade, Daniel J., Thomas, Pamela, Thorpe, Jim, Yao, Gang, Drewes, Gerard, Wagner, Denisa D., Thompson, Paul R., Prinjha, Rab K., Wilson, David M.
Cyhoeddwyd yn Nat Chem Biol (2015)