Nuclear DNA Sensor IFI16 as Circulating Protein in Autoimmune Diseases Is a Signal of Damage that Impairs Endothelial Cells through High-Affinity Membrane Binding

Por Gugliesi, Francesca, Bawadekar, Mandar, De Andrea, Marco, Dell’Oste, Valentina, Caneparo, Valeria, Tincani, Angela, Gariglio, Marisa, Landolfo, Santo
Publicado em 2013

The Extracellular IFI16 Protein Propagates Inflammation in Endothelial Cells Via p38 MAPK and NF-κB p65 Activation

Por Bawadekar, Mandar, De Andrea, Marco, Lo Cigno, Irene, Baldanzi, Gianluca, Caneparo, Valeria, Graziani, Andrea, Landolfo, Santo, Gariglio, Marisa
Publicado no J Interferon Cytokine Res (2015)

DNA Area and NETosis Analysis (DANA): a High-Throughput Method to Quantify Neutrophil Extracellular Traps in Fluorescent Microscope Images

Por Rebernick, Ryan, Fahmy, Lauren, Glover, Christopher, Bawadekar, Mandar, Shim, Daeun, Holmes, Caitlyn L., Rademacher, Nicole, Potluri, Hemanth, Bartels, Christie M., Shelef, Miriam A.
Publicado no Biol Proced Online (2018)

Innate Nuclear Sensor IFI16 Translocates into the Cytoplasm during the Early Stage of In Vitro Human Cytomegalovirus Infection and Is Entrapped in the Egressing Virions during the...

Por Dell'Oste, Valentina, Gatti, Deborah, Gugliesi, Francesca, De Andrea, Marco, Bawadekar, Mandar, Lo Cigno, Irene, Biolatti, Matteo, Vallino, Marta, Marschall, Manfred, Gariglio, Marisa, Landolfo, Santo
Publicado em 2014

Tumor necrosis factor alpha, citrullination, and peptidylarginine deiminase 4 in lung and joint inflammation

Por Bawadekar, Mandar, Gendron-Fitzpatrick, Annette, Rebernick, Ryan, Shim, Daeun, Warner, Thomas F., Nicholas, Anthony P., Lundblad, Lennart K. A., Thompson, Paul R., Shelef, Miriam A.
Publicado no Arthritis Res Ther (2016)

Peptidylarginine Deiminase 2 is Required for Tumor Necrosis Factor Alpha-Induced Citrullination and Arthritis, but Not Neutrophil Extracellular Trap Formation

Por Bawadekar, Mandar, Shim, Daeun, Johnson, Chad J., Warner, Thomas F., Rebernick, Ryan, Damgaard, Dres, Nielsen, Claus H., Pruijn, Ger J. M., Nett, Jeniel E., Shelef, Miriam A.
Publicado no J Autoimmun (2017)

Citrullination of NF-kB p65 enhances its nuclear localization and TLR-induced expression of IL-1β and TNFα

Por Sun, Bo, Dwivedi, Nishant, Bechtel, Tyler J., Paulsen, Janet L., Muth, Aaron, Bawadekar, Mandar, Li, Gang, Thompson, Paul R., Shelef, Miriam A., Schiffer, Celia A., Weerapana, Eranthie, Ho, I-Cheng
Publicado no Sci Immunol (2017)