Citrullination of NF-kB p65 enhances its nuclear localization and TLR-induced expression of IL-1β and TNFα

Citrullination converts peptidyl-arginine to peptidyl-citrulline and is mediated by the enzymes peptidyl arginine deiminases (PADs), including PAD1–4 and PAD6. The physiological role of citrullination in immune cells is poorly understood. Here we report that suppression of PAD activity attenuates TL...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Immunol
Main Authors: Sun, Bo, Dwivedi, Nishant, Bechtel, Tyler J., Paulsen, Janet L., Muth, Aaron, Bawadekar, Mandar, Li, Gang, Thompson, Paul R., Shelef, Miriam A., Schiffer, Celia A., Weerapana, Eranthie, Ho, I-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718838/
https://ncbi.nlm.nih.gov/pubmed/28783661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aal3062
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados