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Detection and Identification of Protein Citrullination in Complex Biological Systems

Protein citrullination is a post-translational modification of arginine that is catalyzed by the Protein Arginine Deiminase (PAD) family of enzymes. Aberrantly increased citrullination is associated with a host of inflammatory diseases and cancer and PAD inhibitors have shown remarkable efficacy in...

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Veröffentlicht in:Curr Opin Chem Biol
Hauptverfasser: Clancy, Kathleen W., Weerapana, Eranthie, Thompson, Paul R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731267/
https://ncbi.nlm.nih.gov/pubmed/26517730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2015.10.014
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