Reciprocal regulation of Th2 and Th17 cells by PAD2-mediated citrullination

Dysregulated citrullination, a unique form of posttranslational modification catalyzed by the peptidylarginine deiminases (PADs), has been observed in several human diseases, including rheumatoid arthritis. However, the physiological roles of PADs in the immune system are still poorly understood. He...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Sun, Bo, Chang, Hui-Hsin, Salinger, Ari, Tomita, Beverly, Bawadekar, Mandar, Holmes, Caitlyn L., Shelef, Miriam A., Weerapana, Eranthie, Thompson, Paul R., Ho, I-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948856/
https://ncbi.nlm.nih.gov/pubmed/31723060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.129687
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