Peptidylarginine Deiminase 2 is Required for Tumor Necrosis Factor Alpha-Induced Citrullination and Arthritis, but Not Neutrophil Extracellular Trap Formation

Citrullination, the post-translational conversion of arginines to citrullines, may contribute to rheumatoid arthritis development given the generation of anti-citrullinated protein antibodies (ACPAs). However, it is not known which peptidylarginine deiminase (PAD) catalyzes the citrullination seen i...

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Detalhes bibliográficos
Publicado no:J Autoimmun
Main Authors: Bawadekar, Mandar, Shim, Daeun, Johnson, Chad J., Warner, Thomas F., Rebernick, Ryan, Damgaard, Dres, Nielsen, Claus H., Pruijn, Ger J. M., Nett, Jeniel E., Shelef, Miriam A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5422119/
https://ncbi.nlm.nih.gov/pubmed/28188029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2017.01.006
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