MON-708 Characterizing DNA Methylation Signatures in Adipose Tissue from Metabolic Impaired Asymptomatic Individuals

Autor Escalante-Araiza, Fabiola, Barajas-Olmos, Francisco, Martínez-Hernández, Angélica, Huerta-Ávila, Eira, Peschard, Vanessa-Giselle, Rodríguez-Ayala, Ernesto, Bastarrachea, Raul A, Orozco, Lorena
Vydáno v J Endocr Soc (2020)

Next-generation sequencing for identifying a novel/de novo pathogenic variant in a Mexican patient with cystic fibrosis: a case report

Autor Martínez-Hernández, Angélica, Larrosa, Julieta, Barajas-Olmos, Francisco, García-Ortíz, Humberto, Mendoza-Caamal, Elvia C., Contreras-Cubas, Cecilia, Mirzaeicheshmeh, Elaheh, Lezana, José Luis, Orozco, Lorena
Vydáno v BMC Med Genomics (2019)

Comparing signals of natural selection between three Indigenous North American populations

Autor Reynolds, Austin W., Mata-Míguez, Jaime, Miró-Herrans, Aida, Briggs-Cloud, Marcus, Sylestine, Ana, Barajas-Olmos, Francisco, Garcia-Ortiz, Humberto, Rzhetskaya, Margarita, Orozco, Lorena, Raff, Jennifer A., Hayes, M. Geoffrey, Bolnick, Deborah A.
Vydáno v Proc Natl Acad Sci U S A (2019)

Variation in Actionable Pharmacogenetic Markers in Natives and Mestizos From Mexico

Autor Gonzalez-Covarrubias, Vanessa, Morales-Franco, Marlet, Cruz-Correa, Omar F., Martínez-Hernández, Angélica, García-Ortíz, Humberto, Barajas-Olmos, Francisco, Genis-Mendoza, Alma Delia, Martínez-Magaña, José Jaime, Nicolini, Humberto, Orozco, Lorena, Soberón, Xavier
Vydáno v Front Pharmacol (2019)

Altered DNA methylation in liver and adipose tissues derived from individuals with obesity and type 2 diabetes

Autor Barajas-Olmos, Francisco, Centeno-Cruz, Federico, Zerrweck, Carlos, Imaz-Rosshandler, Iván, Martínez-Hernández, Angélica, Cordova, Emilio J., Rangel-Escareño, Claudia, Gálvez, Faustino, Castillo, Armando, Maydón, Hernán, Campos, Francisco, Maldonado-Pintado, Diana Gabriela, Orozco, Lorena
Vydáno v BMC Med Genet (2018)

Catalytically Impaired TYK2 Variants are Protective Against Childhood- and Adult-Onset Systemic Lupus Erythematosus in Mexicans

Autor Contreras-Cubas, Cecilia, García-Ortiz, Humberto, Velázquez-Cruz, Rafael, Barajas-Olmos, Francisco, Baca, Paulina, Martínez-Hernández, Angélica, Barbosa-Cobos, Rosa Elda, Ramírez-Bello, Julian, López-Hernández, Maria A., Svyryd, Yevgeniya, Mutchinick, Osvaldo M., Baca, Vicente, Orozco, Lorena
Vydáno v Sci Rep (2019)

Whole genome variation in 27 Mexican indigenous populations, demographic and biomedical insights

Autor Aguilar-Ordoñez, Israel, Pérez-Villatoro, Fernando, García-Ortiz, Humberto, Barajas-Olmos, Francisco, Ballesteros-Villascán, Judith, González-Buenfil, Ram, Fresno, Cristobal, Garcíarrubio, Alejandro, Fernández-López, Juan Carlos, Tovar, Hugo, Hernández-Lemus, Enrique, Orozco, Lorena, Soberón, Xavier, Morett, Enrique
Vydáno v PLoS One (2021)

Two novel variants in DYRK1B causative of AOMS3: expanding the clinical spectrum

Autor Mendoza-Caamal, Elvia C., Barajas-Olmos, Francisco, Mirzaeicheshmeh, Elaheh, Ilizaliturri-Flores, Ian, Aguilar-Salinas, Carlos A., Gómez-Velasco, Donaji V., Cicerón-Arellano, Isabel, Reséndiz-Rodríguez, Adriana, Martínez-Hernández, Angélica, Contreras-Cubas, Cecilia, Islas-Andrade, Sergio, Zerrweck, Carlos, García-Ortiz, Humberto, Orozco, Lorena
Vydáno v Orphanet J Rare Dis (2021)

Heterogenous Distribution of MTHFR Gene Variants among Mestizos and Diverse Amerindian Groups from Mexico

Autor Contreras-Cubas, Cecilia, Sánchez-Hernández, Beatríz E., García-Ortiz, Humberto, Martínez-Hernández, Angélica, Barajas-Olmos, Francisco, Cid, Miguel, Mendoza-Caamal, Elvia C., Centeno-Cruz, Federico, Ortiz-Cruz, Gabriela, Jiménez-López, José Concepción, Córdova, Emilio J., Salas-Bautista, Eva Gabriela, Saldaña-Alvarez, Yolanda, Fernández-López, Juan Carlos, Mutchinick, Osvaldo M., Orozco, Lorena
Vydáno v PLoS One (2016)

Genetic variability of five ADRB2 polymorphisms among Mexican Amerindian ethnicities and the Mestizo population

Autor Salas-Martínez, María Guadalupe, Saldaña-Alvarez, Yolanda, Cordova, Emilio J., Mendiola-Soto, Diana Karen, Cid-Soto, Miguel A., Luckie-Duque, Angélica, Vicenteño-Ayala, Hermenegildo, Barajas-Olmos, Francisco, Contreras-Cubas, Cecilia, García-Ortiz, Humberto, Jiménez-Ruíz, Juan L., Centeno-Cruz, Federico, Martínez-Hernández, Angélica, Mendoza-Caamal, Elvia C., Mirzaeicheshmeh, Elaheh, Orozco, Lorena
Vydáno v PLoS One (2019)

Metabolic syndrome in indigenous communities in Mexico: a descriptive and cross-sectional study

Autor Mendoza-Caamal, Elvia Cristina, Barajas-Olmos, Francisco, García-Ortiz, Humberto, Cicerón-Arellano, Isabel, Martínez-Hernández, Angélica, Córdova, Emilio J., Esparza-Aguilar, Marcelino, Contreras-Cubas, Cecilia, Centeno-Cruz, Federico, Cid-Soto, Miguel, Morales-Marín, Mirna Edith, Reséndiz-Rodríguez, Adriana, Jiménez-Ruiz, Juan Luis, Salas-Martínez, María Guadalupe, Saldaña-Alvarez, Yolanda, Mirzaeicheshmeh, Elaheh, Rojas-Martínez, María Rosalba, Orozco, Lorena
Vydáno v BMC Public Health (2020)

Reconstruction of ancient microbial genomes from the human gut

Autor Wibowo, Marsha C., Yang, Zhen, Borry, Maxime, Hübner, Alexander, Huang, Kun D., Tierney, Braden T., Zimmerman, Samuel, Barajas-Olmos, Francisco, Contreras-Cubas, Cecilia, García-Ortiz, Humberto, Martínez-Hernández, Angélica, Luber, Jacob M., Kirstahler, Philipp, Blohm, Tre, Smiley, Francis E., Arnold, Richard, Ballal, Sonia A., Pamp, Sünje Johanna, Russ, Julia, Maixner, Frank, Rota-Stabelli, Omar, Segata, Nicola, Reinhard, Karl, Orozco, Lorena, Warinner, Christina, Snow, Meradeth, LeBlanc, Steven, Kostic, Aleksandar D.
Vydáno v Nature (2021)

Deep Multi-OMICs and Multi-Tissue Characterization in a Pre- and Postprandial State in Human Volunteers: The GEMM Family Study Research Design

Autor Bastarrachea, Raul A., Laviada-Molina, Hugo A., Nava-Gonzalez, Edna J., Leal-Berumen, Irene, Escudero-Lourdes, Claudia, Escalante-Araiza, Fabiola, Peschard, Vanessa-Giselle, Veloz-Garza, Rosa A., Haack, Karin, Martínez-Hernández, Angélica, Barajas-Olmos, Francisco M., Molina-Segui, Fernanda, Buenfil-Rello, Fatima A., Gonzalez-Ramirez, Lucia, Janssen-Aguilar, Reinhard, Lopez-Muñoz, Ricardo, Perez-Cetina, Fernanda, Gaytan-Saucedo, Janeth F., Vaquera, Zoila, Cornejo-Barrera, Judith, Castillo-Pineda, Juan Carlos, Murillo-Ramirez, Areli, Diaz-Tena, Sara P., Figueroa-Nuñez, Benigno, González-López, Laura, Salinas-Osornio, Rocío A., Valencia-Rendón, Melesio E., Ángeles-Chimal, José, Santa-Olalla Tapia, Jesús, Remes-Troche, José M., Valdovinos-Chavez, Salvador B., Huerta-Avila, Eira E., Han, Xianlin, Orozco, Lorena, Rodriguez-Ayala, Ernesto, Weintraub, Susan, Gallegos-Cabrales, Esther C., Cole, Shelley A., Kent, Jack W.
Vydáno v Genes (Basel) (2018)

Towards precision medicine: defining and characterizing adipose tissue dysfunction to identify early immunometabolic risk in symptom-free adults from the GEMM family study

Autor Rodriguez-Ayala, Ernesto, Gallegos-Cabrales, Esther C., Gonzalez-Lopez, Laura, Laviada-Molina, Hugo A., Salinas-Osornio, Rocio A., Nava-Gonzalez, Edna J., Leal-Berumen, Irene, Escudero-Lourdes, Claudia, Escalante-Araiza, Fabiola, Buenfil-Rello, Fatima A., Peschard, Vanessa-Giselle, Laviada-Nagel, Antonio, Silva, Eliud, Veloz-Garza, Rosa A., Martinez-Hernandez, Angelica, Barajas-Olmos, Francisco M., Molina-Segui, Fernanda, Gonzalez-Ramirez, Lucia, Espadas-Olivera, Rebeca, Lopez-Muñoz, Ricardo, Arjona-Villicaña, Ruy D., Hernandez-Escalante, Victor M., Rodriguez-Arellano, Martha E., Gaytan-Saucedo, Janeth F., Vaquera, Zoila, Acebo-Martinez, Monica, Cornejo-Barrera, Judith, Jancy Andrea, Huertas-Quintero, Castillo-Pineda, Juan Carlos, Murillo-Ramirez, Areli, Diaz-Tena, Sara P., Figueroa-Nuñez, Benigno, Valencia-Rendon, Melesio E., Garzon-Zamora, Rafael, Viveros-Paredes, Juan Manuel, Ángeles-Chimal, José, Santa-Olalla Tapia, Jesús, Remes-Troche, José M., Valdovinos-Chavez, Salvador B., Huerta-Avila, Eira E., Lopez-Alvarenga, Juan Carlos, Comuzzie, Anthony G, Haack, Karin, Han, Xianlin, Orozco, Lorena, Weintraub, Susan, Kent, Jack W., Cole, Shelley A., Bastarrachea, Raul A.
Vydáno v Adipocyte (2020)

A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes

Autor Mercader, Josep M., Liao, Rachel G., Bell, Avery D., Dymek, Zachary, Estrada, Karol, Tukiainen, Taru, Huerta-Chagoya, Alicia, Moreno-Macías, Hortensia, Jablonski, Kathleen A., Hanson, Robert L., Walford, Geoffrey A., Moran, Ignasi, Chen, Ling, Agarwala, Vineeta, Ordoñez-Sánchez, María Luisa, Rodríguez-Guillen, Rosario, Rodríguez-Torres, Maribel, Segura-Kato, Yayoi, García-Ortiz, Humberto, Centeno-Cruz, Federico, Barajas-Olmos, Francisco, Caulkins, Lizz, Puppala, Sobha, Fontanillas, Pierre, Williams, Amy L., Bonàs-Guarch, Sílvia, Hartl, Chris, Ripke, Stephan, Tooley, Katherine, Lane, Jacqueline, Zerrweck, Carlos, Martínez-Hernández, Angélica, Córdova, Emilio J., Mendoza-Caamal, Elvia, Contreras-Cubas, Cecilia, González-Villalpando, María E., Cruz-Bautista, Ivette, Muñoz-Hernández, Liliana, Gómez-Velasco, Donaji, Alvirde, Ulises, Henderson, Brian E., Wilkens, Lynne R., Le Marchand, Loic, Arellano-Campos, Olimpia, Riba, Laura, Harden, Maegan, Gabriel, Stacey, Abboud, Hanna E., Cortes, Maria L., Revilla-Monsalve, Cristina, Islas-Andrade, Sergio, Soberon, Xavier, Curran, Joanne E., Jenkinson, Christopher P., DeFronzo, Ralph A., Lehman, Donna M., Hanis, Craig L., Bell, Graeme I., Boehnke, Michael, Blangero, John, Duggirala, Ravindranath, Saxena, Richa, MacArthur, Daniel, Ferrer, Jorge, McCarroll, Steven A., Torrents, David, Knowler, William C., Baier, Leslie J., Burtt, Noel, González-Villalpando, Clicerio, Haiman, Christopher A., Aguilar-Salinas, Carlos A., Tusié-Luna, Teresa, Flannick, Jason, Jacobs, Suzanne B.R., Orozco, Lorena, Altshuler, David, Florez, Jose C.
Vydáno v Diabetes (2017)

Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes

Autor Goodrich, Julia K., Singer-Berk, Moriel, Son, Rachel, Sveden, Abigail, Wood, Jordan, England, Eleina, Cole, Joanne B., Weisburd, Ben, Watts, Nick, Caulkins, Lizz, Dornbos, Peter, Koesterer, Ryan, Zappala, Zachary, Zhang, Haichen, Maloney, Kristin A., Dahl, Andy, Aguilar-Salinas, Carlos A., Atzmon, Gil, Barajas-Olmos, Francisco, Barzilai, Nir, Blangero, John, Boerwinkle, Eric, Bonnycastle, Lori L., Bottinger, Erwin, Bowden, Donald W., Centeno-Cruz, Federico, Chambers, John C., Chami, Nathalie, Chan, Edmund, Chan, Juliana, Cheng, Ching-Yu, Cho, Yoon Shin, Contreras-Cubas, Cecilia, Córdova, Emilio, Correa, Adolfo, DeFronzo, Ralph A., Duggirala, Ravindranath, Dupuis, Josée, Garay-Sevilla, Ma Eugenia, García-Ortiz, Humberto, Gieger, Christian, Glaser, Benjamin, González-Villalpando, Clicerio, Gonzalez, Ma Elena, Grarup, Niels, Groop, Leif, Gross, Myron, Haiman, Christopher, Han, Sohee, Hanis, Craig L., Hansen, Torben, Heard-Costa, Nancy L., Henderson, Brian E., Hernandez, Juan Manuel Malacara, Hwang, Mi Yeong, Islas-Andrade, Sergio, Jørgensen, Marit E., Kang, Hyun Min, Kim, Bong-Jo, Kim, Young Jin, Koistinen, Heikki A., Kooner, Jaspal Singh, Kuusisto, Johanna, Kwak, Soo-Heon, Laakso, Markku, Lange, Leslie, Lee, Jong-Young, Lee, Juyoung, Lehman, Donna M., Linneberg, Allan, Liu, Jianjun, Loos, Ruth J. F., Lyssenko, Valeriya, Ma, Ronald C. W., Martínez-Hernández, Angélica, Meigs, James B., Meitinger, Thomas, Mendoza-Caamal, Elvia, Mohlke, Karen L., Morris, Andrew D., Morrison, Alanna C., Ng, Maggie C. Y., Nilsson, Peter M., O’Donnell, Christopher J., Orozco, Lorena, Palmer, Colin N. A., Park, Kyong Soo, Post, Wendy S., Pedersen, Oluf, Preuss, Michael, Psaty, Bruce M., Reiner, Alexander P., Revilla-Monsalve, Cristina, Rich, Stephen S., Rotter, Jerome I., Saleheen, Danish, Schurmann, Claudia, Sim, Xueling, Sladek, Rob, Small, Kerrin S., So, Wing Yee, Spector, Timothy D., Strauch, Konstantin, Strom, Tim M., Tai, E. Shyong, Tam, Claudia H. T., Teo, Yik Ying, Thameem, Farook, Tomlinson, Brian, Tracy, Russell P., Tuomi, Tiinamaija, Tuomilehto, Jaakko, Tusié-Luna, Teresa, van Dam, Rob M., Vasan, Ramachandran S., Wilson, James G., Witte, Daniel R., Wong, Tien-Yin, Burtt, Noël P., Zaitlen, Noah, McCarthy, Mark I., Boehnke, Michael, Pollin, Toni I., Flannick, Jason, Mercader, Josep M., O’Donnell-Luria, Anne, Baxter, Samantha, Florez, Jose C., MacArthur, Daniel G., Udler, Miriam S.
Vydáno v Nat Commun (2021)

Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls

Autor Flannick, Jason, Mercader, Josep M., Fuchsberger, Christian, Udler, Miriam S., Mahajan, Anubha, Wessel, Jennifer, Teslovich, Tanya M., Caulkins, Lizz, Koesterer, Ryan, Barajas-Olmos, Francisco, Blackwell, Thomas W., Boerwinkle, Eric, Brody, Jennifer A., Centeno-Cruz, Federico, Chen, Ling, Chen, Siying, Contreras-Cubas, Cecilia, Córdova, Emilio, Correa, Adolfo, Cortes, Maria, DeFronzo, Ralph A., Dolan, Lawrence, Drews, Kimberly L., Elliott, Amanda, Floyd, James S., Gabriel, Stacey, Garay-Sevilla, Maria Eugenia, García-Ortiz, Humberto, Gross, Myron, Han, Sohee, Heard-Costa, Nancy L., Jackson, Anne U., Jørgensen, Marit E., Kang, Hyun Min, Kelsey, Megan, Kim, Bong-Jo, Koistinen, Heikki A., Kuusisto, Johanna, Leader, Joseph B., Linneberg, Allan, Liu, Ching-Ti, Liu, Jianjun, Lyssenko, Valeriya, Manning, Alisa K., Marcketta, Anthony, Malacara-Hernandez, Juan Manuel, Martínez-Hernández, Angélica, Matsuo, Karen, Mayer-Davis, Elizabeth, Mendoza-Caamal, Elvia, Mohlke, Karen L., Morrison, Alanna C., Ndungu, Anne, Ng, Maggie C. Y., O’Dushlaine, Colm, Payne, Anthony J., Pihoker, Catherine, Post, Wendy S., Preuss, Michael, Psaty, Bruce M., Vasan, Ramachandran S., Rayner, N. William, Reiner, Alexander P., Revilla-Monsalve, Cristina, Robertson, Neil R., Santoro, Nicola, Schurmann, Claudia, So, Wing Yee, Soberón, Xavier, Stringham, Heather M., Strom, Tim M., Tam, Claudia H. T., Thameem, Farook, Tomlinson, Brian, Torres, Jason M., Tracy, Russell P., van Dam, Rob M., Vujkovic, Marijana, Wang, Shuai, Welch, Ryan P., Witte, Daniel R., Wong, Tien-Yin, Atzmon, Gil, Barzilai, Nir, Blangero, John, Bonnycastle, Lori L., Bowden, Donald W., Chambers, John C., Chan, Edmund, Cheng, Ching-Yu, Cho, Yoon Shin, Collins, Francis S., de Vries, Paul S., Duggirala, Ravindranath, Glaser, Benjamin, Gonzalez, Clicerio, Gonzalez, Ma Elena, Groop, Leif, Kooner, Jaspal Singh, Kwak, Soo Heon, Laakso, Markku, Lehman, Donna M., Nilsson, Peter, Spector, Timothy D., Tai, E. Shyong, Tuomi, Tiinamaija, Tuomilehto, Jaakko, Wilson, James G., Aguilar-Salinas, Carlos A., Bottinger, Erwin, Burke, Brian, Carey, David J., Chan, Juliana C. N., Dupuis, Josée, Frossard, Philippe, Heckbert, Susan R., Hwang, Mi Yeong, Kim, Young Jin, Kirchner, H. Lester, Lee, Jong-Young, Lee, Juyoung, Loos, Ruth J. F., Ma, Ronald C. W., Morris, Andrew D., O’Donnell, Christopher J., Palmer, Colin N. A., Pankow, James, Park, Kyong Soo, Rasheed, Asif, Saleheen, Danish, Sim, Xueling, Small, Kerrin S., Teo, Yik Ying, Haiman, Christopher, Hanis, Craig L., Henderson, Brian E., Orozco, Lorena, Tusié-Luna, Teresa, Dewey, Frederick E., Baras, Aris, Gieger, Christian, Meitinger, Thomas, Strauch, Konstantin, Lange, Leslie, Grarup, Niels, Hansen, Torben, Pedersen, Oluf, Zeitler, Philip, Dabelea, Dana, Abecasis, Goncalo, Bell, Graeme I., Cox, Nancy J., Seielstad, Mark, Sladek, Rob, Meigs, James B., Rich, Steve S., Rotter, Jerome I., Altshuler, David, Burtt, Noël P., Scott, Laura J., Morris, Andrew P., Florez, Jose C., McCarthy, Mark I., Boehnke, Michael
Vydáno v Nature (2019)