Heterogenous Distribution of MTHFR Gene Variants among Mestizos and Diverse Amerindian Groups from Mexico

Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in folate metabolism. Folate deficiency has been related to several conditions, including neural tube defects (NTDs) and cardiovascular diseases. Hence, MTHFR genetic variants have been studied worldwide, particularly the C677T and A1298C....

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Publicado en:PLoS One
Autores principales: Contreras-Cubas, Cecilia, Sánchez-Hernández, Beatríz E., García-Ortiz, Humberto, Martínez-Hernández, Angélica, Barajas-Olmos, Francisco, Cid, Miguel, Mendoza-Caamal, Elvia C., Centeno-Cruz, Federico, Ortiz-Cruz, Gabriela, Jiménez-López, José Concepción, Córdova, Emilio J., Salas-Bautista, Eva Gabriela, Saldaña-Alvarez, Yolanda, Fernández-López, Juan Carlos, Mutchinick, Osvaldo M., Orozco, Lorena
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029802/
https://ncbi.nlm.nih.gov/pubmed/27649570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163248
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