Heterogenous Distribution of MTHFR Gene Variants among Mestizos and Diverse Amerindian Groups from Mexico

Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in folate metabolism. Folate deficiency has been related to several conditions, including neural tube defects (NTDs) and cardiovascular diseases. Hence, MTHFR genetic variants have been studied worldwide, particularly the C677T and A1298C....

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Publicat a:PLoS One
Autors principals: Contreras-Cubas, Cecilia, Sánchez-Hernández, Beatríz E., García-Ortiz, Humberto, Martínez-Hernández, Angélica, Barajas-Olmos, Francisco, Cid, Miguel, Mendoza-Caamal, Elvia C., Centeno-Cruz, Federico, Ortiz-Cruz, Gabriela, Jiménez-López, José Concepción, Córdova, Emilio J., Salas-Bautista, Eva Gabriela, Saldaña-Alvarez, Yolanda, Fernández-López, Juan Carlos, Mutchinick, Osvaldo M., Orozco, Lorena
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029802/
https://ncbi.nlm.nih.gov/pubmed/27649570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163248
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