New insights into the causes of thrombotic events in patients with myeloproliferative neoplasms raise the possibility of novel therapeutic approaches

Por Bar-Natan, Michal, Hoffman, Ronald
Publicado no Haematologica (2019)

STAT signaling in the pathogenesis and treatment of myeloid malignancies

Por Bar-Natan, Michal, Nelson, Erik A., Xiang, Michael, Frank, David A.
Publicado em 2012

The STAT5 inhibitor pimozide decreases survival of chronic myelogenous leukemia cells resistant to kinase inhibitors

Por Nelson, Erik A., Walker, Sarah R., Weisberg, Ellen, Bar-Natan, Michal, Barrett, Rosemary, Gashin, Laurie B., Terrell, Shariya, Klitgaard, Josephine L., Santo, Loredana, Addorio, Martha R., Ebert, Benjamin L., Griffin, James D., Frank, David A.
Publicado em 2011

The STAT5 Inhibitor Pimozide Displays Efficacy in Models of Acute Myelogenous Leukemia Driven by FLT3 Mutations

Por Nelson, Erik A., Walker, Sarah R., Xiang, Michael, Weisberg, Ellen, Bar-Natan, Michal, Barrett, Rosemary, Liu, Suiyang, Kharbanda, Surender, Christie, Amanda L., Nicolais, Maria, Griffin, James D., Stone, Richard M., Kung, Andrew L., Frank, David A.
Publicado em 2012

Mucin 1 is a potential therapeutic target in cutaneous T-cell lymphoma

Por Jain, Salvia, Stroopinsky, Dina, Yin, Li, Rosenblatt, Jacalyn, Alam, Maroof, Bhargava, Parul, Clark, Rachael A., Kupper, Thomas S., Palmer, Kristen, Coll, Maxwell D., Rajabi, Hasan, Pyzer, Athalia, Bar-Natan, Michal, Luptakova, Katarina, Arnason, Jon, Joyce, Robin, Kufe, Donald, Avigan, David
Publicado no Blood (2015)

TET2 mutations predict response to hypomethylating agents in myelodysplastic syndrome patients

Por Bejar, Rafael, Lord, Allegra, Stevenson, Kristen, Bar-Natan, Michal, Pérez-Ladaga, Albert, Zaneveld, Jacques, Wang, Hui, Caughey, Bennett, Stojanov, Petar, Getz, Gad, Garcia-Manero, Guillermo, Kantarjian, Hagop, Chen, Rui, Stone, Richard M., Neuberg, Donna, Steensma, David P., Ebert, Benjamin L.
Publicado em 2014

Bone marrow stroma protects myeloma cells from cytotoxic damage via induction of the oncoprotein MUC1

Por Bar-Natan, Michal, Stroopinsky, Dina, Luptakova, Katarina, Coll, Maxwell D., Apel, Arie, Rajabi, Hasan, Pyzer, Athalia R., Palmer, Kristen, Reagan, Michaela R., Nahas, Myrna R., Leaf, Rebecca Karp, Jain, Salvia, Arnason, Jon, Ghobrial, Irene M., Anderson, Kenneth C., Kufe, Donald, Rosenblatt, Jacalyn, Avigan, David
Publicado no Br J Haematol (2017)

MUC1‐C drives myeloid leukaemogenesis and resistance to treatment by a survivin‐mediated mechanism

Por Stroopinsky, Dina, Rajabi, Hasan, Nahas, Myrna, Rosenblatt, Jacalyn, Rahimian, Maryam, Pyzer, Athalia, Tagde, Ashujit, Kharbanda, Akriti, Jain, Salvia, Kufe, Turner, Leaf, Rebecca K., Anastasiadou, Eleni, Bar‐Natan, Michal, Orr, Shira, Coll, Maxwell D., Palmer, Kristen, Ephraim, Adam, Cole, Leandra, Washington, Abigail, Kufe, Donald, Avigan, David
Publicado no J Cell Mol Med (2018)

A Genome-Wide Aberrant RNA Splicing in Patients with Acute Myeloid Leukemia Identifies Novel Potential Disease Markers and Therapeutic Targets

Por Adamia, Sophia, Haibe-Kains, Benjamin, Pilarski, Patrick M., Bar-Natan, Michal, Pevzner, Samuel, Avet-Loiseau, Herve, Lode, Laurence, Verselis, Sigitas, Fox, Edward A., Burke, John, Galinsky, Ilene, Dagogo-Jack, Ibiayi, Wadleigh, Martha, Steensma, David P., Motyckova, Gabriela, Deangelo, Daniel J., Quackenbush, John, Stone, Richard, Griffin, James D.
Publicado no Clin Cancer Res (2013)

Low SATB1 Expression Promotes IL-5 and IL-9 Expression in Sézary Syndrome

Por Herrera, Alberto, Fredholm, Simon, Cheng, Anthony, Mimitou, Eleni P., Seffens, Angelina, Bar-Natan, Michal, Sun, Amy, Latkowski, Jo-Ann, Willerslew-Olsen, Andreas, Buus, Terkild B., Gluud, Maria, Krejsgaard, Thorbjørn, Torres-Rusillo, Sara, Bonefeld, Charlotte Menné, Woetmann, Anders, Geisler, Carsten, Geskin, Larisa J., Ouyang, Zhengqing, Smibert, Peter, Ødum, Niels, Koralov, Sergei B.
Publicado no J Invest Dermatol (2019)

NOTCH2 and FLT3 gene mis-splicings are common events in patients with acute myeloid leukemia (AML): new potential targets in AML

Por Adamia, Sophia, Bar-Natan, Michal, Haibe-Kains, Benjamin, Pilarski, Patrick M., Bach, Christian, Pevzner, Samuel, Calimeri, Teresa, Avet-Loiseau, Herve, Lode, Laurence, Verselis, Sigitas, Fox, Edward A., Galinsky, Ilene, Mathews, Steven, Dagogo-Jack, Ibiayi, Wadleigh, Martha, Steensma, David P., Motyckova, Gabriela, Deangelo, Daniel J., Quackenbush, John, Tenen, Daniel G., Stone, Richard M., Griffin, James D.
Publicado em 2014

Gene expression–based discovery of atovaquone as a STAT3 inhibitor and anticancer agent

Por Xiang, Michael, Kim, Haesook, Ho, Vincent T., Walker, Sarah R., Bar-Natan, Michal, Anahtar, Melodi, Liu, Suhu, Toniolo, Patricia A., Kroll, Yasmin, Jones, Nichole, Giaccone, Zachary T., Heppler, Lisa N., Ye, Darwin Q., Marineau, Jason J., Shaw, Daniel, Bradner, James E., Blonquist, Traci, Neuberg, Donna, Hetz, Claudio, Stone, Richard M., Soiffer, Robert J., Frank, David A.
Publicado no Blood (2016)

Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia

Por Yoda, Akinori, Yoda, Yuka, Chiaretti, Sabina, Bar-Natan, Michal, Mani, Kartik, Rodig, Scott J., West, Nathan, Xiao, Yun, Brown, Jennifer R., Mitsiades, Constantine, Sattler, Martin, Kutok, Jeffrey L., DeAngelo, Daniel J., Wadleigh, Martha, Piciocchi, Alfonso, Dal Cin, Paola, Bradner, James E., Griffin, James D., Anderson, Kenneth C., Stone, Richard M., Ritz, Jerome, Foà, Robin, Aster, Jon C., Frank, David A., Weinstock, David M.
Publicado em 2009

TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups

Por Haase, Detlef, Stevenson, Kristen E., Neuberg, Donna, Maciejewski, Jaroslaw P., Nazha, Aziz, Sekeres, Mikkael A., Ebert, Benjamin L., Garcia-Manero, Guillermo, Haferlach, Claudia, Haferlach, Torsten, Kern, Wolfgang, Ogawa, Seishi, Nagata, Yasunobu, Yoshida, Kenichi, Graubert, Timothy A., Walter, Matthew J., List, Alan F., Komrokji, Rami S., Padron, Eric, Sallman, David, Papaemmanuil, Elli, Campbell, Peter J., Savona, Michael R., Seegmiller, Adam, Adès, Lionel, Fenaux, Pierre, Shih, Lee-Yung, Bowen, David, Groves, Michael J., Tauro, Sudhir, Fontenay, Michaela, Kosmider, Olivier, Bar-Natan, Michal, Steensma, David, Stone, Richard, Heuser, Michael, Thol, Felicitas, Cazzola, Mario, Malcovati, Luca, Karsan, Aly, Ganster, Christina, Hellström-Lindberg, Eva, Boultwood, Jacqueline, Pellagatti, Andrea, Santini, Valeria, Quek, Lynn, Vyas, Paresh, Tüchler, Heinz, Greenberg, Peter L., Bejar, Rafael
Publicado no Leukemia (2019)

Special considerations in the management of adult patients with acute leukaemias and myeloid neoplasms in the COVID-19 era: recommendations from a panel of international experts

Por Zeidan, Amer M, Boddu, Prajwal C, Patnaik, Mrinal M, Bewersdorf, Jan Philipp, Stahl, Maximilian, Rampal, Raajit K, Shallis, Rory, Steensma, David P, Savona, Michael R, Sekeres, Mikkael A, Roboz, Gail J, DeAngelo, Daniel J, Schuh, Andre C, Padron, Eric, Zeidner, Joshua F, Walter, Roland B, Onida, Francesco, Fathi, Amir, DeZern, Amy, Hobbs, Gabriela, Stein, Eytan M, Vyas, Paresh, Wei, Andrew H, Bowen, David T, Montesinos, Pau, Griffiths, Elizabeth A, Verma, Amit K, Keyzner, Alla, Bar-Natan, Michal, Navada, Shyamala C, Kremyanskaya, Marina, Goldberg, Aaron D, Al-Kali, Aref, Heaney, Mark L, Nazha, Aziz, Salman, Huda, Luger, Selina, Pratz, Keith W, Konig, Heiko, Komrokji, Rami, Deininger, Michael, Cirici, Blanca Xicoy, Bhatt, Vijaya Raj, Silverman, Lewis R, Erba, Harry P, Fenaux, Pierre, Platzbecker, Uwe, Santini, Valeria, Wang, Eunice S, Tallman, Martin S, Stone, Richard M, Mascarenhas, John
Publicado no Lancet Haematol (2020)