Evidence that the plant cannabinoid Δ(9)-tetrahydrocannabivarin is a cannabinoid CB(1) and CB(2) receptor antagonist

di Thomas, Adèle, Stevenson, Lesley A, Wease, Kerrie N, Price, Martin R, Baillie, Gemma, Ross, Ruth A, Pertwee, Roger G
Pubblicazione 2005

Modulation of l-α-Lysophosphatidylinositol/GPR55 Mitogen-activated Protein Kinase (MAPK) Signaling by Cannabinoids

di Anavi-Goffer, Sharon, Baillie, Gemma, Irving, Andrew J., Gertsch, Jürg, Greig, Iain R., Pertwee, Roger G., Ross, Ruth A.
Pubblicazione 2012

Phosphorylation of ezrin on Thr567 is required for the synergistic activation of cell spreading by EPAC1 and protein kinase A in HEK293T cells

di Parnell, Euan, Koschinski, Andreas, Zaccolo, Manuela, Cameron, Ryan T., Baillie, George S., Baillie, Gemma L., Porter, Alison, McElroy, Stuart P., Yarwood, Stephen J.
Pubblicato in Biochim Biophys Acta (2015)

Identification of a Novel, Small Molecule Partial Agonist for the Cyclic AMP Sensor, EPAC1

di Parnell, Euan, McElroy, Stuart P., Wiejak, Jolanta, Baillie, Gemma L., Porter, Alison, Adams, David R., Rehmann, Holger, Smith, Brian O., Yarwood, Stephen J.
Pubblicato in Sci Rep (2017)

The F238L Point Mutation in the Cannabinoid Type 1 Receptor Enhances Basal Endocytosis via Lipid Rafts

di Wickert, Melanie, Hildick, Keri L., Baillie, Gemma L., Jelinek, Ruth, Aparisi Rey, Alejandro, Monory, Krisztina, Schneider, Miriam, Ross, Ruth A., Henley, Jeremy M., Lutz, Beat
Pubblicato in Front Mol Neurosci (2018)

Allosteric Modulation of a Cannabinoid G Protein-coupled Receptor: BINDING SITE ELUCIDATION AND RELATIONSHIP TO G PROTEIN SIGNALING

di Shore, Derek M., Baillie, Gemma L., Hurst, Dow H., Navas, Frank, Seltzman, Herbert H., Marcu, Jahan P., Abood, Mary E., Ross, Ruth A., Reggio, Patricia H.
Pubblicazione 2014

CB(1) Receptor Allosteric Modulators Display Both Agonist and Signaling Pathway Specificity

di Baillie, Gemma L., Horswill, James G., Anavi-Goffer, Sharon, Reggio, Patricia H., Bolognini, Daniele, Abood, Mary E., McAllister, Sean, Strange, Phillip G., Stephens, Gary J., Pertwee, Roger G., Ross, Ruth A.
Pubblicazione 2013

The Trifluoromethyl Group as a Bioisosteric Replacement of the Aliphatic Nitro Group in CB(1) Receptor Positive Allosteric Modulators

di Tseng, Chih-Chung, Baillie, Gemma, Donvito, Giulia, Mustafa, Mohammed A., Juola, Sophie E., Zanato, Chiara, Massarenti, Chiara, Dall’Angelo, Sergio, Harrison, William T. A., Lichtman, Aron H., Ross, Ruth A., Zanda, Matteo, Greig, Iain R.
Pubblicato in J Med Chem (2019)

A Cannabinoid CB(1) Receptor-Positive Allosteric Modulator Reduces Neuropathic Pain in the Mouse with No Psychoactive Effects

di Ignatowska-Jankowska, Bogna M, Baillie, Gemma L, Kinsey, Steven, Crowe, Molly, Ghosh, Sudeshna, Owens, Robert A, Damaj, Imad M, Poklis, Justin, Wiley, Jenny L, Zanda, Matteo, Zanato, Chiara, Greig, Iain R, Lichtman, Aron H, Ross, Ruth A
Pubblicato in Neuropsychopharmacology (2015)

Synthesis and Structure‐Activity Relationships of N‐(4‐Benzamidino)‐Oxazolidinones: Potent and Selective Inhibitors of Kallikrein‐Related Peptidase 6

di De Vita, Elena, Smits, Niels, van den Hurk, Helma, Beck, Elizabeth M., Hewitt, Joanne, Baillie, Gemma, Russell, Emily, Pannifer, Andrew, Hamon, Véronique, Morrison, Angus, McElroy, Stuart P., Jones, Philip, Ignatenko, Natalia A., Gunkel, Nikolas, Miller, Aubry K.
Pubblicato in ChemMedChem (2019)

Pregnenolone Can Protect the Brain from Cannabis Intoxication

di Vallée, Monique, Vitiello, Sergio, Bellocchio, Luigi, Hébert-Chatelain, Etienne, Monlezun, Stéphanie, Martin-Garcia, Elena, Kasanetz, Fernando, Baillie, Gemma L., Panin, Francesca, Cathala, Adeline, Roullot-Lacarrière, Valérie, Fabre, Sandy, Hurst, Dow P., Lynch, Diane L., Shore, Derek M., Deroche-Gamonet, Véronique, Spampinato, Umberto, Revest, Jean-Michel, Maldonado, Rafael, Reggio, Patricia H., Ross, Ruth A., Marsicano, Giovanni, Piazza, Pier Vincenzo
Pubblicazione 2014