A Cannabinoid CB(1) Receptor-Positive Allosteric Modulator Reduces Neuropathic Pain in the Mouse with No Psychoactive Effects

The CB(1) receptor represents a promising target for the treatment of several disorders including pain-related disease states. However, therapeutic applications of Δ(9)-tetrahydrocannabinol and other CB(1) orthosteric receptor agonists remain limited because of psychoactive side effects. Positive al...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Ignatowska-Jankowska, Bogna M, Baillie, Gemma L, Kinsey, Steven, Crowe, Molly, Ghosh, Sudeshna, Owens, Robert A, Damaj, Imad M, Poklis, Justin, Wiley, Jenny L, Zanda, Matteo, Zanato, Chiara, Greig, Iain R, Lichtman, Aron H, Ross, Ruth A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864630/
https://ncbi.nlm.nih.gov/pubmed/26052038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.148
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