A Cannabinoid CB(1) Receptor-Positive Allosteric Modulator Reduces Neuropathic Pain in the Mouse with No Psychoactive Effects

The CB(1) receptor represents a promising target for the treatment of several disorders including pain-related disease states. However, therapeutic applications of Δ(9)-tetrahydrocannabinol and other CB(1) orthosteric receptor agonists remain limited because of psychoactive side effects. Positive al...

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Publicado en:Neuropsychopharmacology
Autores principales: Ignatowska-Jankowska, Bogna M, Baillie, Gemma L, Kinsey, Steven, Crowe, Molly, Ghosh, Sudeshna, Owens, Robert A, Damaj, Imad M, Poklis, Justin, Wiley, Jenny L, Zanda, Matteo, Zanato, Chiara, Greig, Iain R, Lichtman, Aron H, Ross, Ruth A
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2015
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864630/
https://ncbi.nlm.nih.gov/pubmed/26052038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.148
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