A Cannabinoid CB(1) Receptor-Positive Allosteric Modulator Reduces Neuropathic Pain in the Mouse with No Psychoactive Effects

The CB(1) receptor represents a promising target for the treatment of several disorders including pain-related disease states. However, therapeutic applications of Δ(9)-tetrahydrocannabinol and other CB(1) orthosteric receptor agonists remain limited because of psychoactive side effects. Positive al...

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Détails bibliographiques
Publié dans:Neuropsychopharmacology
Auteurs principaux: Ignatowska-Jankowska, Bogna M, Baillie, Gemma L, Kinsey, Steven, Crowe, Molly, Ghosh, Sudeshna, Owens, Robert A, Damaj, Imad M, Poklis, Justin, Wiley, Jenny L, Zanda, Matteo, Zanato, Chiara, Greig, Iain R, Lichtman, Aron H, Ross, Ruth A
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864630/
https://ncbi.nlm.nih.gov/pubmed/26052038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.148
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