Fetal Hemoglobin Inducers from the Natural World: A Novel Approach for Identification of Drugs for the Treatment of β-Thalassemia and Sickle-Cell Anemia

Por Bianchi, Nicoletta, Zuccato, Cristina, Lampronti, Ilaria, Borgatti, Monica, Gambari, Roberto
Publicado em 2009

Born at 27 weeks of gestation with classical PKU: challenges of dietetic management in a very preterm infant

Por Ballhausen, Diana, Egli, Delphine, Bickle-Graz, Myriam, Bianchi, Nicoletta, Bonafé, Luisa
Publicado em 2011

Inhibitory Effects of Bangladeshi Medicinal Plant Extracts on Interactions between Transcription Factors and Target DNA Sequences

Por Lampronti, Ilaria, Khan, Mahmud T.H., Borgatti, Monica, Bianchi, Nicoletta, Gambari, Roberto
Publicado em 2008

Erythroid induction of K562 cells treated with mithramycin is associated with inhibition of raptor gene transcription and mammalian target of rapamycin complex 1 (mTORC1) functions

Por Finotti, Alessia, Bianchi, Nicoletta, Fabbri, Enrica, Borgatti, Monica, Breveglieri, Giulia, Gasparello, Jessica, Gambari, Roberto
Publicado no Pharmacol Res (2015)

Bergamot (Citrus bergamia Risso) fruit extracts and identified components alter expression of interleukin 8 gene in cystic fibrosis bronchial epithelial cell lines

Por Borgatti, Monica, Mancini, Irene, Bianchi, Nicoletta, Guerrini, Alessandra, Lampronti, Ilaria, Rossi, Damiano, Sacchetti, Gianni, Gambari, Roberto
Publicado em 2011

Targeting pre-miRNA by Peptide Nucleic Acids: A new strategy to interfere in the miRNA maturation

Por Avitabile, Concetta, Saviano, Michele, D'Andrea, Luca, Bianchi, Nicoletta, Fabbri, Enrica, Brognara, Eleonora, Gambari, Roberto, Romanelli, Alessandra
Publicado em 2012

Recent trends in the gene therapy of β-thalassemia

Por Finotti, Alessia, Breda, Laura, Lederer, Carsten W, Bianchi, Nicoletta, Zuccato, Cristina, Kleanthous, Marina, Rivella, Stefano, Gambari, Roberto
Publicado no J Blood Med (2015)

Cellular Uptakes, Biostabilities and Anti-miR-210 Activities of Chiral Arginine-PNAs in Leukaemic K562 Cells

Por Manicardi, Alex, Fabbri, Enrica, Tedeschi, Tullia, Sforza, Stefano, Bianchi, Nicoletta, Brognara, Eleonora, Gambari, Roberto, Marchelli, Rosangela, Corradini, Roberto
Publicado em 2012

A combined approach for β-thalassemia based on gene therapy-mediated adult hemoglobin (HbA) production and fetal hemoglobin (HbF) induction

Por Zuccato, Cristina, Breda, Laura, Salvatori, Francesca, Breveglieri, Giulia, Gardenghi, Sara, Bianchi, Nicoletta, Brognara, Eleonora, Lampronti, Ilaria, Borgatti, Monica, Rivella, Stefano, Gambari, Roberto
Publicado em 2012

Increase of microRNA-210, Decrease of Raptor Gene Expression and Alteration of Mammalian Target of Rapamycin Regulated Proteins following Mithramycin Treatment of Human Erythroid C...

Por Bianchi, Nicoletta, Finotti, Alessia, Ferracin, Manuela, Lampronti, Ilaria, Zuccato, Cristina, Breveglieri, Giulia, Brognara, Eleonora, Fabbri, Enrica, Borgatti, Monica, Negrini, Massimo, Gambari, Roberto
Publicado no PLoS One (2015)

Development and characterization of K562 cell clones expressing BCL11A-XL: Decreased hemoglobin production with fetal hemoglobin inducers and its rescue with mithramycin

Por Finotti, Alessia, Gasparello, Jessica, Breveglieri, Giulia, Cosenza, Lucia Carmela, Montagner, Giulia, Bresciani, Alberto, Altamura, Sergio, Bianchi, Nicoletta, Martini, Elisa, Gallerani, Eleonora, Borgatti, Monica, Gambari, Roberto
Publicado no Exp Hematol (2015)

Development of K562 cell clones expressing β-globin mRNA carrying the β(0)39 thalassaemia mutation for the screening of correctors of stop-codon mutations

Por Salvatori, Francesca, Cantale, Vera, Breveglieri, Giulia, Zuccato, Cristina, Finotti, Alessia, Bianchi, Nicoletta, Borgatti, Monica, Feriotto, Giordana, Destro, Federica, Canella, Alessandro, Breda, Laura, Rivella, Stefano, Gambari, Roberto
Publicado em 2009

Production of β-globin and adult hemoglobin following G418 treatment of erythroid precursor cells from homozygous β(0)39 thalassemia patients

Por Salvatori, Francesca, Breveglieri, Giulia, Zuccato, Cristina, Finotti, Alessia, Bianchi, Nicoletta, Borgatti, Monica, Feriotto, Giordana, Destro, Federica, Canella, Alessandro, Brognara, Eleonora, Lampronti, Ilaria, Breda, Laura, Rivella, Stefano, Gambari, Roberto
Publicado em 2009

Peptide nucleic acids targeting β-globin mRNAs selectively inhibit hemoglobin production in murine erythroleukemia cells

Por MONTAGNER, GIULIA, GEMMO, CHIARA, FABBRI, ENRICA, MANICARDI, ALEX, ACCARDO, IGEA, BIANCHI, NICOLETTA, FINOTTI, ALESSIA, BREVEGLIERI, GIULIA, SALVATORI, FRANCESCA, BORGATTI, MONICA, LAMPRONTI, ILARIA, BRESCIANI, ALBERTO, ALTAMURA, SERGIO, CORRADINI, ROBERTO, GAMBARI, ROBERTO
Publicado no Int J Mol Med (2015)

Regulation of IL-8 gene expression in gliomas by microRNA miR-93

Por Fabbri, Enrica, Brognara, Eleonora, Montagner, Giulia, Ghimenton, Claudio, Eccher, Albino, Cantù, Cinzia, Khalil, Susanna, Bezzerri, Valentino, Provezza, Lisa, Bianchi, Nicoletta, Finotti, Alessia, Borgatti, Monica, Moretto, Giuseppe, Chilosi, Marco, Cabrini, Giulio, Gambari, Roberto
Publicado no BMC Cancer (2015)

A validated cellular biobank for β-thalassemia

Por Cosenza, Lucia Carmela, Breda, Laura, Breveglieri, Giulia, Zuccato, Cristina, Finotti, Alessia, Lampronti, Ilaria, Borgatti, Monica, Chiavilli, Francesco, Gamberini, Maria Rita, Satta, Stefania, Manunza, Laura, De Martis, Franca Rosa, Moi, Paolo, Rivella, Stefano, Gambari, Roberto, Bianchi, Nicoletta
Publicado no J Transl Med (2016)

Generation and Characterization of a Transgenic Mouse Carrying a Functional Human β-Globin Gene with the IVSI-6 Thalassemia Mutation

Por Breveglieri, Giulia, Mancini, Irene, Bianchi, Nicoletta, Lampronti, Ilaria, Salvatori, Francesca, Fabbri, Enrica, Zuccato, Cristina, Cosenza, Lucia C., Montagner, Giulia, Borgatti, Monica, Altruda, Fiorella, Fagoonee, Sharmila, Carandina, Gianni, Rubini, Michele, Aiello, Vincenzo, Breda, Laura, Rivella, Stefano, Gambari, Roberto, Finotti, Alessia
Publicado no Biomed Res Int (2015)

Therapeutic Hemoglobin Levels after Gene Transfer in β-Thalassemia Mice and in Hematopoietic Cells of β-Thalassemia and Sickle Cells Disease Patients

Por Breda, Laura, Casu, Carla, Gardenghi, Sara, Bianchi, Nicoletta, Cartegni, Luca, Narla, Mohandas, Yazdanbakhsh, Karina, Musso, Marco, Manwani, Deepa, Little, Jane, Gardner, Lawrence B., Kleinert, Dorothy A., Prus, Eugenia, Fibach, Eitan, Grady, Robert W., Giardina, Patricia J., Gambari, Roberto, Rivella, Stefano
Publicado em 2012