A carregar...

Erythroid induction of K562 cells treated with mithramycin is associated with inhibition of raptor gene transcription and mammalian target of rapamycin complex 1 (mTORC1) functions

Rapamycin, an inhibitor of mTOR activity, is a potent inducer of erythroid differentiation and fetal hemoglobin production in β-thalassemic patients. Mithramycin (MTH) was studied to see if this inducer of K562 differentiation also operates through inhibition of mTOR. We can conclude from the study...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Pharmacol Res
Main Authors: Finotti, Alessia, Bianchi, Nicoletta, Fabbri, Enrica, Borgatti, Monica, Breveglieri, Giulia, Gasparello, Jessica, Gambari, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309890/
https://ncbi.nlm.nih.gov/pubmed/25478892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2014.11.005
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!