Natural Products as Topoisomerase II Poisons: Effects of Thymoquinone on DNA Cleavage Mediated by Human Topoisomerase IIα

le Ashley, Rachel E., Osheroff, Neil
Foilsithe 2014

Recognition of DNA Supercoil Geometry by Mycobacterium tuberculosis Gyrase

le Ashley, Rachel E., Blower, Tim R., Berger, James M., Osheroff, Neil
Foilsithe in Biochemistry (2017)

Oxidative transformation of demethoxy- and bisdemethoxycurcumin: Products, mechanism of formation, and poisoning of human topoisomerase IIα

le Gordon, Odaine N., Luis, Paula B., Ashley, Rachel E., Osheroff, Neil, Schneider, Claus
Foilsithe in Chem Res Toxicol (2015)

Catalytic Core of Human Topoisomerase IIα: Insights into Enzyme–DNA Interactions and Drug Mechanism

le Lindsey, R. Hunter, Pendleton, MaryJean, Ashley, Rachel E., Mercer, Susan L., Deweese, Joseph E., Osheroff, Neil
Foilsithe 2014

Activities of gyrase and topoisomerase IV on positively supercoiled DNA

le Ashley, Rachel E., Dittmore, Andrew, McPherson, Sylvia A., Turnbough, Charles L., Neuman, Keir C., Osheroff, Neil
Foilsithe in Nucleic Acids Res (2017)

Interactions between Quinolones and Bacillus anthracis Gyrase and the Basis of Drug Resistance

le Ashley, Rachel E., Lindsey, R. Hunter, McPherson, Sylvia A., Turnbough, Charles L., Kerns, Robert J., Osheroff, Neil
Foilsithe in Biochemistry (2017)

Synthesis and evaluation of ether-linked demethylepipodophyllotoxin dimers

le Dunlap, Norma, Salyard, Tracy L. J., Pathiranage, Anuradha Liyana, Stubblefield, Jeannie, Pitts, Steven L., Ashley, Rachel E., Osheroff, Neil
Foilsithe in Bioorg Med Chem Lett (2014)