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Interactions between Quinolones and Bacillus anthracis Gyrase and the Basis of Drug Resistance

[Image: see text] Gyrase appears to be the primary cellular target for quinolone antibacterials in multiple pathogenic bacteria, including Bacillus anthracis, the causative agent of anthrax. Given the significance of this type II topoisomerase as a drug target, it is critical to understand how quino...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Ashley, Rachel E., Lindsey, R. Hunter, McPherson, Sylvia A., Turnbough, Charles L., Kerns, Robert J., Osheroff, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560241/
https://ncbi.nlm.nih.gov/pubmed/28708938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00203
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