Interactions between Quinolones and Bacillus anthracis Gyrase and the Basis of Drug Resistance

[Image: see text] Gyrase appears to be the primary cellular target for quinolone antibacterials in multiple pathogenic bacteria, including Bacillus anthracis, the causative agent of anthrax. Given the significance of this type II topoisomerase as a drug target, it is critical to understand how quino...

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Vydáno v:Biochemistry
Hlavní autoři: Ashley, Rachel E., Lindsey, R. Hunter, McPherson, Sylvia A., Turnbough, Charles L., Kerns, Robert J., Osheroff, Neil
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2017
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560241/
https://ncbi.nlm.nih.gov/pubmed/28708938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00203
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